{"id":"W2971282072","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2397","title":"DNMT3A and TET2 Mutations: Linking Genetics and Epigenetics in Pulmonary Arterial Hypertension","year":2019,"lang":"en","type":"article","venue":"","topic":"Pulmonary Hypertension Research and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Epigenetics; Genetics; Medical genetics; Pulmonary hypertension; Biology; Medicine; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002584789,0.0003021922,0.0002510513,0.0006068049,0.0002337471,0.0005391373,0.0003667276,0.000968207,0.002610279],"category_scores_gemma":[0.001224029,0.0001692624,0.0002353076,0.00062971,0.0004258878,0.0003716107,0.0003966648,0.0005206088,0.0001835712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003320599,"about_ca_system_score_gemma":0.0003097686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001571941,"about_ca_topic_score_gemma":0.001872398,"domain_scores_codex":[0.9997573,0.00006381042,0.00002522662,0.00004582559,0.00007767234,0.00003008235],"domain_scores_gemma":[0.9995078,0.0002108909,0.0001710533,0.00002699295,0.00003784391,0.00004535223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002801416,0.0002729713,0.4950545,0.0004353569,0.0008322771,0.02937184,0.0005611501,0.002292863,0.291387,0.01288619,0.004487111,0.1596173],"study_design_scores_gemma":[0.0002169016,0.0005566445,0.7651641,0.0002727372,0.001142778,0.1046194,0.0008036033,0.009845302,0.07680637,0.01620954,0.02427787,0.00008473713],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9649299,0.01837428,0.003866392,0.005148408,0.0001915189,0.00001950911,0.0006041938,0.0001446814,0.006720982],"genre_scores_gemma":[0.9960201,0.002008573,0.0007876863,0.0002125077,0.0001129269,0.000003476375,0.00006220724,0.00000932989,0.000783229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002610279,"threshold_uncertainty_score":0.0087322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02414086903164936,"score_gpt":0.2745343458342511,"score_spread":0.2503934768026018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}