{"id":"W2971334346","doi":"10.1186/s12885-019-6018-1","title":"Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane","year":2019,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Queen's University; Hospital for Sick Children","funders":"Associazione Italiana per la Ricerca sul Cancro; Cancer Research Society","keywords":"Cancer research; Population; Homeobox protein NANOG; Cell culture; Pathology; Spheroid; Matrigel; Medicine; Biology; Angiogenesis; Induced pluripotent stem cell; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007607567,0.0001017058,0.0001321343,0.00001441559,0.00005218223,0.00001121505,0.0001138433,0.00005344731,0.00002904946],"category_scores_gemma":[0.00001643419,0.0000845468,0.00004350493,0.00003621814,0.00008674799,0.000003530832,0.00007084951,0.00006340677,0.000001315893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001263439,"about_ca_system_score_gemma":0.00003757787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001331452,"about_ca_topic_score_gemma":0.0001728167,"domain_scores_codex":[0.9993901,0.00003715892,0.0001520403,0.0002062172,0.00007601184,0.0001384585],"domain_scores_gemma":[0.9995421,0.00001120001,0.0001712983,0.0001742616,0.00007122949,0.00002987133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002739945,0.00001981118,0.05416163,0.00005200027,0.00001741993,7.541556e-8,0.00006054523,0.00002467625,0.9441258,0.00001886594,0.001420333,0.00007141307],"study_design_scores_gemma":[0.0007358693,0.00007357444,0.04749032,0.00001708839,0.00001320742,7.243327e-7,0.0002069167,0.00003242976,0.9504031,0.00005121095,0.0008663287,0.0001092223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973317,0.001803557,0.00003859562,0.00003227459,0.0001168246,0.0002260197,0.0001384506,0.000003658554,0.0003089142],"genre_scores_gemma":[0.999191,0.0000468632,0.00006467573,0.0001553446,0.0001070949,0.00002120039,0.0000908811,0.0000135236,0.0003093429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006671308,"threshold_uncertainty_score":0.3447719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00870131308333013,"score_gpt":0.2410648052128967,"score_spread":0.2323634921295666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}