{"id":"W2971408301","doi":"10.3390/pathogens8030139","title":"Characterization and Protective Activity of Monoclonal Antibodies Directed against Streptococcus suis Serotype 2 Capsular Polysaccharide Obtained Using a Glycoconjugate","year":2019,"lang":"en","type":"article","venue":"Pathogens","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; Université du Québec à Montréal; Cegep de Saint Hyacinthe; Université de Montréal; University of Alberta","funders":"Canadian Glycomics Network; Fonds de recherche du Québec – Nature et technologies; Networks of Centres of Excellence of Canada; Natural Sciences and Engineering Research Council of Canada; International Development Research Centre","keywords":"Streptococcus suis; Serotype; Microbiology; Monoclonal antibody; Glycoconjugate; Antibody; Biology; Pathogen; Immunization; Polysaccharide; Antibody opsonization; Virology; Opsonin; Virulence; Immunology; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016315,0.0004607829,0.0001758498,0.0002720366,0.00007947549,0.0001581448,0.0001399264,0.0002303562,0.0005095726],"category_scores_gemma":[0.0001960022,0.00009504523,0.0002847103,0.0001252519,0.00009015392,0.000101645,0.0001118491,0.0002862623,0.0001622884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001739835,"about_ca_system_score_gemma":0.0001289935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005547707,"about_ca_topic_score_gemma":0.0005039032,"domain_scores_codex":[0.999892,0.00002347192,0.000008559156,0.00001596714,0.00002650248,0.00003347794],"domain_scores_gemma":[0.9999094,0.00002021953,0.00001471462,0.00001076513,0.00002568352,0.00001934084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004562092,0.00003473163,0.000338581,0.0000166214,0.000004974604,0.00002597912,0.000007060864,0.0000456807,0.9982256,0.00001801903,0.00001394738,0.001223152],"study_design_scores_gemma":[0.00004429093,0.001970548,0.01737782,0.00001243473,0.00006482953,0.0004356712,0.00002270684,0.001165948,0.9757532,0.00004088541,0.003105733,0.000005952881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967332,0.0007050039,0.001576252,0.00002637782,0.00001513266,0.00002594595,0.000107912,0.00002225174,0.000787974],"genre_scores_gemma":[0.9958283,0.0005492535,0.001682255,0.00007140875,0.00001530245,0.00002855306,0.0007739773,0.000008629601,0.001042185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005547707,"threshold_uncertainty_score":0.001704633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01873704053075266,"score_gpt":0.2706998398373885,"score_spread":0.2519627993066359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}