{"id":"W2971408301","doi":"10.3390/pathogens8030139","title":"Characterization and Protective Activity of Monoclonal Antibodies Directed against Streptococcus suis Serotype 2 Capsular Polysaccharide Obtained Using a Glycoconjugate","year":2019,"lang":"en","type":"article","venue":"Pathogens","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; Université du Québec à Montréal; Cegep de Saint Hyacinthe; Université de Montréal; University of Alberta","funders":"Canadian Glycomics Network; Fonds de recherche du Québec – Nature et technologies; Networks of Centres of Excellence of Canada; Natural Sciences and Engineering Research Council of Canada; International Development Research Centre","keywords":"Streptococcus suis; Serotype; Microbiology; Monoclonal antibody; Glycoconjugate; Antibody; Biology; Pathogen; Immunization; Polysaccharide; Antibody opsonization; Virology; Opsonin; Virulence; Immunology; Phagocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000772589,0.0001953194,0.0003861199,0.0001470338,0.00008566656,0.00001569287,0.00002781296,0.00009826112,0.00006174771],"category_scores_gemma":[0.00006099131,0.0001690661,0.00009099074,0.0002585554,0.00005407237,0.0001299321,0.00004371085,0.0001137626,0.000008961342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008132326,"about_ca_system_score_gemma":0.00008088477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002703872,"about_ca_topic_score_gemma":0.00001510679,"domain_scores_codex":[0.9990477,0.00006169622,0.0002089076,0.0003282879,0.0001407287,0.0002127094],"domain_scores_gemma":[0.9992654,0.00003127332,0.0001804785,0.0002353238,0.0001924734,0.00009500047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000128723,0.0001299512,0.4092879,0.00005100162,0.0001382166,0.00001257647,0.0001293484,0.00000533775,0.587388,0.000008697705,1.783863e-7,0.002720095],"study_design_scores_gemma":[0.001145438,0.0002533982,0.6767654,0.0001188766,0.0001299094,0.00001738761,0.00003934856,0.004084865,0.3172911,0.00001581643,0.00001496937,0.0001234834],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970618,0.00003611674,0.0004022518,0.00002398812,0.00008206058,0.001986332,0.0001772464,0.00008761752,0.0001425144],"genre_scores_gemma":[0.9992004,0.00003160123,0.0004587983,0.00001774963,0.00004191027,0.00007675024,0.00006347053,0.00002495878,0.00008433252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2700969,"threshold_uncertainty_score":0.6894316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01873704053075266,"score_gpt":0.2706998398373885,"score_spread":0.2519627993066359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}