{"id":"W2971428495","doi":"10.1038/s41398-019-0592-5","title":"Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer’s disease","year":2019,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Norwegian Institute of Public Health; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Helse Sør-Øst RHF; IXICO; Genentech; Sykehuset Innlandet HF; H. Lundbeck A/S; Servier; King's College London; University of Exeter; Meso Scale Diagnostics; Department of Health and Social Care; National Institute on Aging; National Institute for Health and Care Research; Northern California Institute for Research and Education; Eisai; South London and Maudsley NHS Foundation Trust; Norges Teknisk-Naturvitenskapelige Universitet; University of Pennsylvania; University of Southern California; Pfizer; BioClinica; Biogen; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Alzheimer's Disease Neuroimaging Initiative; Ministero della Salute; Novartis Pharmaceuticals Corporation; Alzheimer's Association","keywords":"Schizophrenia (object-oriented programming); Psychosis; Psychiatry; Disease; Psychology; Cohort; Genome-wide association study; Medicine; Clinical psychology; Internal medicine; Single-nucleotide polymorphism; Genotype","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004470529,0.0005768553,0.0005540274,0.001392048,0.0003087643,0.000827138,0.0004252628,0.0006344767,0.0012102],"category_scores_gemma":[0.006723951,0.0003224307,0.002264437,0.001766783,0.0005504222,0.0003049905,0.0006872611,0.0006216996,0.00009335285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002836645,"about_ca_system_score_gemma":0.0004131139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003866556,"about_ca_topic_score_gemma":0.004127609,"domain_scores_codex":[0.9973173,0.001797755,0.000195107,0.0004228522,0.000194798,0.00007227425],"domain_scores_gemma":[0.9928337,0.005154099,0.001148813,0.0004424379,0.0002349939,0.0001859842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001953992,0.00008214348,0.9345792,0.0007492853,0.03876358,0.0003216768,0.0001211827,0.00137597,0.002400623,0.0005287746,0.0003001713,0.01882336],"study_design_scores_gemma":[0.0002919291,0.0008637654,0.9516916,0.0003840534,0.03564003,0.0006411903,0.0001972716,0.004527045,0.001598286,0.002807628,0.001328986,0.00002817351],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.966167,0.02770801,0.003881584,0.0005933887,0.00007762628,0.0000246367,0.0005497141,0.00002763857,0.00097041],"genre_scores_gemma":[0.9968449,0.002167701,0.0006279489,0.00007437964,0.00003563271,0.000008550222,0.0001498884,0.000003456922,0.00008752011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004470529,"threshold_uncertainty_score":0.02364272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02017512776022363,"score_gpt":0.27726240901,"score_spread":0.2570872812497764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}