{"id":"W2971428495","doi":"10.1038/s41398-019-0592-5","title":"Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer’s disease","year":2019,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Norwegian Institute of Public Health; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Helse Sør-Øst RHF; IXICO; Genentech; Sykehuset Innlandet HF; H. Lundbeck A/S; Servier; King's College London; University of Exeter; Meso Scale Diagnostics; Department of Health and Social Care; National Institute on Aging; National Institute for Health and Care Research; Northern California Institute for Research and Education; Eisai; South London and Maudsley NHS Foundation Trust; Norges Teknisk-Naturvitenskapelige Universitet; University of Pennsylvania; University of Southern California; Pfizer; BioClinica; Biogen; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Alzheimer's Disease Neuroimaging Initiative; Ministero della Salute; Novartis Pharmaceuticals Corporation; Alzheimer's Association","keywords":"Schizophrenia (object-oriented programming); Psychosis; Psychiatry; Disease; Psychology; Cohort; Genome-wide association study; Medicine; Clinical psychology; Internal medicine; Single-nucleotide polymorphism; Genotype","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004106809,0.0001104277,0.0001331994,0.00003423804,0.00006231102,0.0000118143,0.0000970855,0.0001301016,0.00002703681],"category_scores_gemma":[0.00005783944,0.00009511269,0.00006051039,0.00007065674,0.00002854629,0.000003377272,0.00001145125,0.0000745002,0.00001195024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009250359,"about_ca_system_score_gemma":0.00008482113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006930329,"about_ca_topic_score_gemma":0.00006362664,"domain_scores_codex":[0.9990412,0.0001045632,0.0002555962,0.0003119225,0.00009495976,0.0001917289],"domain_scores_gemma":[0.9994774,0.0001350289,0.0001046647,0.0001936793,0.00003214901,0.00005710955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00005990935,0.00002358638,0.9967297,0.000009069987,0.00008330988,1.42534e-8,0.00001735958,0.0004104257,0.0001316512,0.000499059,0.0002670761,0.001768867],"study_design_scores_gemma":[0.001016459,0.00007235958,0.9910299,0.000008242823,0.00007563369,3.048505e-7,0.00001408617,0.0005296149,0.000003653794,0.005421451,0.001714121,0.0001142389],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931951,0.001694828,0.001435862,0.002237419,0.0002328535,0.0005317375,0.00005115914,0.000007953697,0.0006130659],"genre_scores_gemma":[0.9945843,0.00002781894,0.004457915,0.0002215742,0.0002723066,0.00005087747,0.0001111846,0.00002102104,0.0002530308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005699837,"threshold_uncertainty_score":0.3878583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02017512776022363,"score_gpt":0.27726240901,"score_spread":0.2570872812497764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}