{"id":"W2971457003","doi":"10.3390/biom9090460","title":"Inhibition of Rho GTPases in Invertebrate Growth Cones Induces a Switch in Responsiveness to Retinoic Acid","year":2019,"lang":"en","type":"article","venue":"Biomolecules","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Growth cone; Cell biology; Retinoic acid; Retinoid; Biology; CDC42; Axon guidance; Neurite; Cytoskeleton; GTPase; Neuroscience; Axon; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002227502,0.0001413418,0.0002310989,0.0004010579,0.00002514787,0.00002041716,0.0001745123,0.00007083844,0.00002781482],"category_scores_gemma":[0.0005736765,0.0001354357,0.00003947728,0.0009470785,0.00008452486,0.0001755201,0.00009646763,0.0001054211,0.00007809004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003492898,"about_ca_system_score_gemma":0.00007542518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001946605,"about_ca_topic_score_gemma":0.0001118956,"domain_scores_codex":[0.9984904,0.0002432395,0.0003470919,0.0004160635,0.0002489241,0.0002542729],"domain_scores_gemma":[0.9994459,0.0001817547,0.000108998,0.0001638864,0.0000449123,0.00005455461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002730187,0.00006940422,0.008797687,0.00004382684,7.497835e-7,0.00008071036,0.0003063874,0.00001313901,0.9885598,0.001605264,0.00001493733,0.0002351014],"study_design_scores_gemma":[0.0004792803,0.0001882632,0.01235945,0.0002789041,0.000001579935,0.00000663635,0.0001405045,0.00005972553,0.9857091,0.0005869993,0.00003566566,0.0001538722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985675,0.00008238675,0.00002617564,0.0005016351,0.00009290307,0.0003267604,0.000009821504,0.00002295623,0.0003699138],"genre_scores_gemma":[0.9986303,0.000034317,0.00004641765,0.001201481,0.00001385909,0.00002569027,0.000001855931,0.00001567735,0.00003034851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003561759,"threshold_uncertainty_score":0.5522907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03017706200485578,"score_gpt":0.2717141106775882,"score_spread":0.2415370486727324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}