{"id":"W2971459875","doi":"10.1002/mds.27823","title":"Neuronal vulnerability in Parkinson disease: Should the focus be on axons and synaptic terminals?","year":2019,"lang":"en","type":"review","venue":"Movement Disorders","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Innovation Council; Vancouver Coastal Health; Université de Montréal","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Fundación BBVA; Michael J. Fox Foundation for Parkinson's Research","keywords":"Neurodegeneration; Neuroscience; Dopaminergic; Parkinson's disease; Dopamine; Disease; Biology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002789996,0.0006475337,0.001255438,0.0002100201,0.0001259075,0.00005135088,0.0002084962,0.0001627491,0.0001738761],"category_scores_gemma":[0.00008966745,0.0004038686,0.0004759135,0.0002264243,0.0001155231,0.00005198272,0.0001340893,0.0005056018,0.00004201482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002813995,"about_ca_system_score_gemma":0.0002619775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001134283,"about_ca_topic_score_gemma":0.000120887,"domain_scores_codex":[0.997241,0.0002699268,0.0005126725,0.0009258701,0.0005577609,0.0004928333],"domain_scores_gemma":[0.9983572,0.0002597752,0.0002012821,0.0008760494,0.0000165391,0.0002891741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001777356,0.001528028,0.004781531,0.006926185,0.0004916008,0.000112304,0.00003433254,0.000003373766,2.060292e-7,0.0004721986,0.0008237461,0.9846488],"study_design_scores_gemma":[0.001397933,0.0004453828,0.0213448,0.003733235,0.002277668,0.000001048125,0.00003829914,0.00006792508,4.341524e-7,0.002302574,0.9680027,0.0003879851],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004523254,0.9877033,0.000008053355,0.002602362,0.0002263151,0.003817558,0.0002990092,0.00004436285,0.0007758384],"genre_scores_gemma":[0.01597555,0.9798111,0.00001144365,0.002476711,0.00004971018,0.0009768173,0.0001888032,0.00007834738,0.0004315591],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9842608,"threshold_uncertainty_score":0.9998413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06867535974045963,"score_gpt":0.3420033975283338,"score_spread":0.2733280377878741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}