{"id":"W2971508997","doi":"10.1093/biolre/ioz177","title":"Estrous cycle impacts microRNA content in extracellular vesicles that modulate bovine cumulus cell transcripts during in vitro maturation","year":2019,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Faculdade de Zootecnia e Engenharia de Alimentos, Universidade de São Paulo; Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Université Laval","keywords":"Biology; Oocyte; Cell biology; Estrous cycle; microRNA; Follicular fluid; Ovarian follicle; Follicular phase; Oogenesis; Follicle; Extracellular vesicle; Microvesicles; Andrology; Gene; Endocrinology; Embryo; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005800943,0.0002148093,0.0004714794,0.0002554113,0.00004615263,0.000006059206,0.0001419252,0.0003114016,0.000045532],"category_scores_gemma":[0.00005533697,0.0001961383,0.00009379056,0.0001668888,0.0001315604,0.000178843,0.00003108996,0.0002685975,0.0000960303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008551155,"about_ca_system_score_gemma":0.0000359715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008251118,"about_ca_topic_score_gemma":0.00002959988,"domain_scores_codex":[0.9977978,0.000403835,0.0005472552,0.000844484,0.00003283445,0.0003737981],"domain_scores_gemma":[0.9989712,0.00002513675,0.0003084819,0.0006114185,0.00006724633,0.00001650968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001358059,0.0001724865,0.04877185,0.000147439,0.0000311767,0.000004624333,0.0007078433,0.00008691471,0.9460474,0.00002290132,0.00001007555,0.002639267],"study_design_scores_gemma":[0.001538115,0.0001667935,0.2380565,0.0000738848,0.000008490356,0.0000810742,0.0002285594,0.000002818535,0.7592283,0.00007372305,0.0003984325,0.0001432701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9344145,0.0626218,0.00003073205,0.0003414204,0.001676356,0.000735913,0.00001346914,0.00003982297,0.0001259685],"genre_scores_gemma":[0.9983457,0.0003212621,0.00009334087,0.000005829138,0.00006325405,0.0000217975,0.0001064018,0.00001868419,0.001023724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1892846,"threshold_uncertainty_score":0.7998287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01949410521208747,"score_gpt":0.2226725558699399,"score_spread":0.2031784506578524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}