{"id":"W2971602650","doi":"10.1038/s41467-019-11978-0","title":"Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":380,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Smoking Research Foundation; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development","keywords":"Gut flora; Polyunsaturated fatty acid; Biology; Arachidonic acid; Linoleic acid; Metabolism; Adipose tissue; Metabolite; Obesity; Fatty acid; Biochemistry; Endocrinology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000169561,0.0001939368,0.0002119588,0.00005538745,0.000281137,0.00004385677,0.001073585,0.0004522554,0.0000235215],"category_scores_gemma":[0.00005959928,0.0001956386,0.00009089315,0.0002591857,0.00009004229,0.000007804432,0.0004470737,0.0006466417,0.0000961094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004029719,"about_ca_system_score_gemma":0.0001327065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003695238,"about_ca_topic_score_gemma":0.0007614079,"domain_scores_codex":[0.9988546,0.0001502734,0.0002297167,0.0003709489,0.00008234032,0.0003121357],"domain_scores_gemma":[0.99745,0.00002816501,0.00009486666,0.002093027,0.0002014384,0.0001324798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004144925,0.00007679618,0.004989059,0.00001443439,0.00004450359,1.57226e-7,0.00005772956,5.469901e-7,0.943974,0.0003501456,0.05039183,0.00005930834],"study_design_scores_gemma":[0.0003528642,0.00004584076,0.1435049,0.00003164887,0.00002584356,0.000004023207,0.00008496994,0.000002847505,0.08043035,0.000005672626,0.775236,0.0002750343],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9476651,0.03528408,0.00007345101,0.01021139,0.0003707273,0.0007433595,0.0005637918,0.00005688388,0.005031239],"genre_scores_gemma":[0.9842585,0.001510132,0.005948915,0.0042182,0.00004286969,0.00001348734,0.001469626,0.0000275311,0.002510768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8635437,"threshold_uncertainty_score":0.7977912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119059363732086,"score_gpt":0.2856583382542324,"score_spread":0.2744677446169116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}