{"id":"W2971602650","doi":"10.1038/s41467-019-11978-0","title":"Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":380,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Smoking Research Foundation; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development","keywords":"Gut flora; Polyunsaturated fatty acid; Biology; Arachidonic acid; Linoleic acid; Metabolism; Adipose tissue; Metabolite; Obesity; Fatty acid; Biochemistry; Endocrinology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001381084,0.0002706277,0.0002584966,0.0002457848,0.00009659385,0.0003015274,0.0001192931,0.0002354881,0.001192757],"category_scores_gemma":[0.0001434865,0.0001286105,0.0001907646,0.0001015375,0.0002045321,0.0001345621,0.0002967123,0.0005586508,0.0001864992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001117038,"about_ca_system_score_gemma":0.0001426862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002116136,"about_ca_topic_score_gemma":0.0003702886,"domain_scores_codex":[0.9998654,0.00004080286,0.000008660257,0.00002377084,0.00002802463,0.00003332301],"domain_scores_gemma":[0.9998839,0.00001084175,0.00003627291,0.00001662227,0.00001039494,0.00004198219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003028627,0.00003435796,0.0006320616,0.00002130295,0.000006821719,0.00003900699,0.000008619951,0.00001955206,0.9968047,0.00006404836,0.00002488095,0.002041743],"study_design_scores_gemma":[0.0001284417,0.002971061,0.05909438,0.00004106152,0.0001107457,0.001015254,0.0001327682,0.001346532,0.9290319,0.0003863534,0.005721748,0.00001976714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955307,0.001414841,0.001487262,0.0002265958,0.00004070994,0.00001475867,0.00009552272,0.00008357854,0.001106057],"genre_scores_gemma":[0.9953054,0.001312508,0.00201606,0.000104633,0.00001913638,0.00001605442,0.00009422911,0.00001760931,0.001114332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001192757,"threshold_uncertainty_score":0.003990114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119059363732086,"score_gpt":0.2856583382542324,"score_spread":0.2744677446169116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}