{"id":"W2971639213","doi":"10.1097/qad.0000000000002360","title":"Pharmacokinetics of maraviroc in plasma and breastmilk in a treatment-experienced perinatally HIV-1-infected woman","year":2019,"lang":"en","type":"letter","venue":"AIDS","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Academy of Medical Sciences; ViiV Healthcare; Wellcome Trust; National Institute for Health and Care Research; Gilead Sciences","keywords":"Medicine; Breastfeeding; Lopinavir; Ritonavir; Breast milk; Maraviroc; Regimen; Pediatrics; Zidovudine; Lamivudine; Lopinavir/ritonavir; Breast feeding; CCR5 receptor antagonist; Internal medicine; Viral load; Immunology; Human immunodeficiency virus (HIV); Antiretroviral therapy; Viral disease; Virus; Chemokine receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002486183,0.0002904952,0.0005850894,0.000287549,0.000338639,0.0005706974,0.0002606266,0.0006936035,0.00111106],"category_scores_gemma":[0.001286644,0.0003005112,0.0002205388,0.0002497273,0.0003033763,0.0002883608,0.0002326101,0.0009076764,0.0004832655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004275359,"about_ca_system_score_gemma":0.0002561241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001290989,"about_ca_topic_score_gemma":0.001387636,"domain_scores_codex":[0.9998349,0.00004007779,0.00001250948,0.00004069603,0.0000466423,0.00002516953],"domain_scores_gemma":[0.9996238,0.0001598564,0.00005860818,0.00001838015,0.00003826524,0.0001010896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.02381694,0.003527305,0.2574988,0.001070801,0.0003939946,0.3360824,0.008092409,0.005085988,0.2067566,0.001443028,0.006080145,0.1501515],"study_design_scores_gemma":[0.0008852299,0.07323461,0.3647226,0.0004550081,0.0009638077,0.3989282,0.00585101,0.02421911,0.07703125,0.00156948,0.05177217,0.0003675843],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899387,0.005029075,0.0007282401,0.0006737773,0.00006295673,0.00005888866,0.0003228022,0.00007635338,0.003109268],"genre_scores_gemma":[0.9957443,0.001788471,0.0007278305,0.00051024,0.00006124459,0.00001508115,0.000187112,0.00002216713,0.000943562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001290989,"threshold_uncertainty_score":0.003716886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01749797658295976,"score_gpt":0.3175229408501585,"score_spread":0.3000249642671987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}