{"id":"W2971699541","doi":"10.1242/dev.148296","title":"RUNX transcription factors: orchestrators of development","year":2019,"lang":"en","type":"review","venue":"Development","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":230,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Horizon 2020 Framework Programme; Medical Research Council Canada; Cancer Research UK","keywords":"Biology; RUNX1; Transcription factor; Embryonic stem cell; Carcinogenesis; Developmental biology; Cell biology; RUNX2; Stem cell; Genetics; Gene; Computational biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004240812,0.0006241885,0.0006796362,0.001418246,0.0002747353,0.0008902182,0.0007834488,0.0006348372,0.002777597],"category_scores_gemma":[0.0003830299,0.0001887221,0.000273089,0.001740792,0.0005959651,0.0009014923,0.0006492655,0.001673414,0.002850555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009643253,"about_ca_system_score_gemma":0.001394348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001075786,"about_ca_topic_score_gemma":0.001534682,"domain_scores_codex":[0.9998449,0.00002177563,0.00001946386,0.00002764331,0.00006806459,0.00001820359],"domain_scores_gemma":[0.9998657,0.00004395166,0.00002346837,0.000005475976,0.00003662226,0.00002488667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000710625,0.00002150102,0.0002542154,0.0048115,0.00003983866,0.0001947413,0.00009092327,0.0004370433,0.005247895,0.01972401,0.04321186,0.9258953],"study_design_scores_gemma":[0.000004626594,0.00001264848,0.0002007844,0.0004094649,0.00001380606,0.0003586941,0.00001836434,0.00002916291,0.0004977339,0.002284501,0.9961641,0.000006032674],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001601758,0.9954854,0.0005439749,0.0006235564,0.0002755278,0.000005517195,0.0000626227,0.00003425821,0.002809016],"genre_scores_gemma":[0.001116344,0.9967086,0.0003941716,0.0002297383,0.0002305693,0.000007043521,0.00009441813,0.000004673713,0.001214456],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002777597,"threshold_uncertainty_score":0.009292006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1502920318887832,"score_gpt":0.3746041553539484,"score_spread":0.2243121234651652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}