{"id":"W2971778440","doi":"10.1104/pp.19.00647","title":"Chemical Screening Pipeline for Identification of Specific Plant Autophagy Modulators","year":2019,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning","keywords":"Autophagy; Arabidopsis; Arabidopsis thaliana; Biology; Cell biology; Computational biology; Programmed cell death; Biochemistry; Gene; Mutant","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009268039,0.0001157919,0.0003547141,0.00006881599,0.00002019951,0.000002683343,0.00009452058,0.0001016184,0.0001539699],"category_scores_gemma":[0.00001790353,0.00009744878,0.0001176266,0.00006360715,0.00004769582,0.00003444969,0.00002694898,0.00008303569,0.00005149622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000014631,"about_ca_system_score_gemma":0.00002762914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004186665,"about_ca_topic_score_gemma":9.887635e-8,"domain_scores_codex":[0.9990857,0.00001786165,0.0003317997,0.0002660797,0.0001049631,0.0001935685],"domain_scores_gemma":[0.9993392,0.0001100812,0.0001516483,0.0002860326,0.00005039379,0.00006260924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001163683,0.0001386607,0.0002467786,0.0001059946,0.00006810616,0.000002736376,0.00005523912,0.00005783893,0.9936466,0.001783596,0.001265181,0.001465566],"study_design_scores_gemma":[0.002531876,0.000154908,0.03285691,0.0000687312,0.0000606599,0.00003238425,0.00004457517,0.02966384,0.9293948,0.001523965,0.003510566,0.0001567448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966205,0.0002939711,0.001836079,0.00006673006,0.0002525453,0.0004449519,0.0003444127,0.00004389578,0.00009693994],"genre_scores_gemma":[0.9974413,0.00006233525,0.0003669699,0.0001414166,0.0002497387,0.00002368434,0.00148116,0.00001698406,0.000216413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06425178,"threshold_uncertainty_score":0.3973846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01889501022334751,"score_gpt":0.2647772743681847,"score_spread":0.2458822641448372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}