{"id":"W2971778440","doi":"10.1104/pp.19.00647","title":"Chemical Screening Pipeline for Identification of Specific Plant Autophagy Modulators","year":2019,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning","keywords":"Autophagy; Arabidopsis; Arabidopsis thaliana; Biology; Cell biology; Computational biology; Programmed cell death; Biochemistry; Gene; Mutant","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007071617,0.001585178,0.001566443,0.002253806,0.0007823212,0.001114776,0.0008450529,0.0009649644,0.01828469],"category_scores_gemma":[0.0006812068,0.0008721078,0.001107386,0.001641012,0.0002899653,0.0007017375,0.001047104,0.001824306,0.01645213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008114073,"about_ca_system_score_gemma":0.002438157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001871321,"about_ca_topic_score_gemma":0.006481907,"domain_scores_codex":[0.9994196,0.0000405227,0.00004135213,0.0001436569,0.000272902,0.00008202518],"domain_scores_gemma":[0.9997398,0.00004087637,0.0000336681,0.00004232171,0.0001033922,0.00003976345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004849274,0.0003492047,0.0009948451,0.001120284,0.0001524152,0.0003357019,0.00007598117,0.0009187788,0.9083918,0.001192816,0.01746011,0.06852321],"study_design_scores_gemma":[0.0003348818,0.001230616,0.005401917,0.0001203416,0.0002416686,0.001250485,0.00006252522,0.005104528,0.797369,0.001001705,0.1877611,0.0001213185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1515529,0.01352175,0.4413424,0.003410864,0.0007341473,0.01403537,0.2331905,0.0661177,0.07609434],"genre_scores_gemma":[0.221003,0.01378733,0.4253304,0.003314881,0.0001571486,0.009253699,0.2808786,0.003036393,0.04323851],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01828469,"threshold_uncertainty_score":0.06116837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01889501022334751,"score_gpt":0.2647772743681847,"score_spread":0.2458822641448372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}