{"id":"W2971786452","doi":"10.1155/2019/7135437","title":"Up-to-Date Tailored Systemic Treatment in Pancreatic Ductal Adenocarcinoma","year":2019,"lang":"en","type":"review","venue":"Gastroenterology Research and Practice","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Servier; National Institute for Health and Care Research; Sanofi; MedImmune; Merck; Royal Marsden NHS Foundation Trust; Amgen; Pfizer; Institute of Cancer Research; Celgene; Bayer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Malignancy; Pancreatic ductal adenocarcinoma; Stroma; Limiting; Immunotherapy; Oncology; Pancreatic cancer; Tumor microenvironment; Intensive care medicine; Internal medicine; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003902674,0.0003641307,0.00102006,0.001102534,0.0001636094,0.0007868737,0.0005078708,0.0006002694,0.003139311],"category_scores_gemma":[0.0004939245,0.0001807728,0.0004668924,0.0009249463,0.0002119538,0.0006927655,0.0004852944,0.001126686,0.001305607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000332363,"about_ca_system_score_gemma":0.0006268941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005444,"about_ca_topic_score_gemma":0.001619293,"domain_scores_codex":[0.9998728,0.00002641361,0.00002068336,0.00002088522,0.00004678623,0.00001230572],"domain_scores_gemma":[0.9998684,0.00007170461,0.00002154066,0.000004622933,0.0000243955,0.000009235172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0000743347,0.0000529329,0.0001105528,0.02306196,0.00009948363,0.0001926009,0.0000438469,0.0002823385,0.00154114,0.001720648,0.01114078,0.9616793],"study_design_scores_gemma":[0.00003580599,0.0001271311,0.0009936577,0.008482107,0.0001960672,0.001692637,0.00005626373,0.0001091298,0.0006356292,0.001345862,0.9863093,0.00001637944],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001737467,0.9986602,0.00007814792,0.000149675,0.00009518517,0.000005183557,0.00001441438,0.000003832148,0.0008195512],"genre_scores_gemma":[0.0008762912,0.998355,0.0001550118,0.0001477447,0.00006911657,0.000005012692,0.00002614565,0.000001102309,0.000364541],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003139311,"threshold_uncertainty_score":0.01050204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2357335899925772,"score_gpt":0.4890493641424871,"score_spread":0.2533157741499099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}