{"id":"W2971806486","doi":"10.1002/pros.23901","title":"Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients","year":2019,"lang":"en","type":"article","venue":"The Prostate","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé","keywords":"Prostate cancer; Microvesicles; Exosome; Extracellular vesicle; Prostate; Glutamate carboxypeptidase II; Prostate-specific antigen; Messenger RNA; Androgen deprivation therapy; Cancer research; Medicine; Internal medicine; Biology; Chemistry; Endocrinology; Cancer; microRNA; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000288501,0.0002308027,0.0001516139,0.00004986733,0.00007405224,0.00004398402,0.0003721609,0.00008028667,0.00009421226],"category_scores_gemma":[0.00005495277,0.000181023,0.00008088006,0.0001671571,0.0001376742,0.00001218778,0.0001954521,0.0001430765,0.0002634918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003923308,"about_ca_system_score_gemma":0.0001180195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009714833,"about_ca_topic_score_gemma":0.00005063342,"domain_scores_codex":[0.9984303,0.0001313882,0.0002989418,0.0004716772,0.0002163009,0.0004514579],"domain_scores_gemma":[0.9991143,0.00001924642,0.0001375925,0.0005606539,0.00006863013,0.00009959853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001168533,0.0002768092,0.1959014,0.00008278358,0.0001334578,0.0000163051,0.0006809877,0.0004757037,0.7888064,0.0001249067,0.0007832876,0.01154944],"study_design_scores_gemma":[0.006212515,0.0006775144,0.0705543,0.0001522598,0.00007856149,0.000008590291,0.0005076382,0.001054312,0.8793874,0.001887519,0.03847508,0.0010043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993882,0.003516588,0.00000431438,0.0002894055,0.0002484164,0.001104468,0.00006411222,0.00002170847,0.0008689815],"genre_scores_gemma":[0.9952947,0.000349447,0.00008662468,0.000192228,0.00005078106,0.0001239804,0.0001316883,0.00005538252,0.003715167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1253471,"threshold_uncertainty_score":0.7381905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004805977538771614,"score_gpt":0.2289074047021382,"score_spread":0.2241014271633665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}