{"id":"W2971877909","doi":"10.1016/j.biomaterials.2019.119477","title":"Injectable and degradable methacrylic acid hydrogel alters macrophage response in skeletal muscle","year":2019,"lang":"en","type":"article","venue":"Biomaterials","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canada First Research Excellence Fund","keywords":"Self-healing hydrogels; Skeletal muscle; Innate immune system; Macrophage; Cell biology; Immune system; M2 Macrophage; Wound healing; Regeneration (biology); Macrophage polarization; Ethylene glycol; Inflammation; Chemistry; Materials science; Biochemistry; Immunology; Biology; Anatomy; In vitro; Polymer chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003228407,0.0003361919,0.0001982638,0.0001614234,0.0001269899,0.0002027085,0.0001713489,0.0003859622,0.001764702],"category_scores_gemma":[0.0001117074,0.000183243,0.0002689702,0.00009058947,0.0002361932,0.0003209166,0.00014267,0.0004116083,0.0002809332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001426861,"about_ca_system_score_gemma":0.0001764902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002145688,"about_ca_topic_score_gemma":0.0004718034,"domain_scores_codex":[0.9998409,0.00003010059,0.00001428974,0.00003627612,0.00002512464,0.00005329687],"domain_scores_gemma":[0.9999034,0.00002483446,0.00002505508,0.000008018859,0.0000115418,0.00002714365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005286497,0.00006681516,0.00008745351,0.00002777159,0.000003156626,0.00002461039,0.00001117523,0.00002160219,0.9986059,0.0000296652,0.00001010675,0.0005830395],"study_design_scores_gemma":[0.00006794632,0.001533928,0.002509026,0.000006386799,0.00002318217,0.00008044545,0.00004204439,0.0003928893,0.9947588,0.00002870128,0.00055312,0.000003588934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975835,0.0007230061,0.0009363227,0.00004617477,0.00005082233,0.00002014938,0.00006709316,0.00001613178,0.0005568073],"genre_scores_gemma":[0.9930883,0.0005170712,0.00183682,0.00007893267,0.00003234926,0.00006188222,0.0001138924,0.00001267954,0.004258113],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001764702,"threshold_uncertainty_score":0.005903542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01640492885666148,"score_gpt":0.2852952482712331,"score_spread":0.2688903194145716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}