{"id":"W2971930116","doi":"10.1101/759852","title":"Ubiquitylated H2A.Z is associated with diverse types of silenced chromatin including methylated CpG islands and homopurine/homopyrimidine sequences","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; York University","funders":"","keywords":"Nucleosome; Chromatin; Histone; Gene silencing; Biology; Ubiquitin; Cell biology; Histone H2A; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001242602,0.0002716978,0.0002545937,0.0003956585,0.0002798356,0.0004381439,0.0002254636,0.0001863465,0.00160352],"category_scores_gemma":[0.000103156,0.0002470008,0.00031436,0.0003133723,0.000243418,0.0001850277,0.0004134639,0.0002302023,0.0004572773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002564276,"about_ca_system_score_gemma":0.0001449194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001299993,"about_ca_topic_score_gemma":0.002236617,"domain_scores_codex":[0.9998211,0.00000991028,0.0000104911,0.00007647638,0.00004175906,0.00004034779],"domain_scores_gemma":[0.9998745,0.000009612079,0.00004937719,0.00001650303,0.00001291987,0.00003722635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008879984,0.000007532439,0.005895912,0.00004737256,0.0000368647,0.00004698983,0.00001813585,0.0000506307,0.9919187,0.00007987546,0.00004345944,0.001765684],"study_design_scores_gemma":[0.00001719198,0.0001090258,0.2441947,0.00001237355,0.00005464914,0.0005692226,0.00007995248,0.001839382,0.7496287,0.0001862372,0.003293993,0.00001450348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903858,0.003026799,0.004622726,0.00004679116,0.0000136333,0.00001025598,0.0007491338,0.00009340457,0.00105161],"genre_scores_gemma":[0.9963439,0.0004432411,0.001030739,0.00004082098,0.000005869893,0.000009528995,0.0007027973,0.00001545414,0.001407682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00160352,"threshold_uncertainty_score":0.005364299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01201505085262049,"score_gpt":0.2209746205783532,"score_spread":0.2089595697257327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}