{"id":"W2971948065","doi":"10.1158/1055-9965.epi-19-0596","title":"A Comprehensive Study of the Effect on Colorectal Cancer Survival of Common Germline Genetic Variation Previously Linked with Cancer Prognosis","year":2019,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"Medical Research Council; China Scholarship Council; Cancer Research UK; Wellcome Trust; Melville Charitable Trust","keywords":"Colorectal cancer; Cancer; Medicine; Germline; Oncology; Internal medicine; Germline mutation; Population; Genetics; Biology; Mutation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001059166,0.000292637,0.0003286582,0.0006944769,0.0003783018,0.0003105249,0.0002301218,0.0002752366,0.001177903],"category_scores_gemma":[0.002145092,0.000156895,0.0005137589,0.001187919,0.0003040585,0.0001929775,0.0005478692,0.0002800198,0.0001500635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002491385,"about_ca_system_score_gemma":0.0006076044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003465089,"about_ca_topic_score_gemma":0.006210873,"domain_scores_codex":[0.9993429,0.0001958565,0.00004845094,0.0002556044,0.00009201109,0.00006515808],"domain_scores_gemma":[0.9982297,0.0005253336,0.0005273533,0.0002780154,0.000160561,0.000279015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004741845,0.00004685384,0.983749,0.00006901671,0.001149386,0.0002273228,0.0001124325,0.0002379782,0.005631573,0.00007722712,0.0002457073,0.007979225],"study_design_scores_gemma":[0.00001902689,0.0002173216,0.9979311,0.00001035653,0.0002935007,0.0003840312,0.00003898945,0.0001454087,0.0003673632,0.00005692072,0.000531594,0.000004355654],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980324,0.0005371904,0.0005206613,0.00004060616,0.000004813149,0.000006922386,0.0006461493,0.000008295052,0.0002030386],"genre_scores_gemma":[0.9985794,0.0001784746,0.0003424571,0.00002912857,0.00001079576,0.000008583603,0.0007147187,0.000004545099,0.0001318854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003465089,"threshold_uncertainty_score":0.00688982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02685464725823643,"score_gpt":0.333409691583039,"score_spread":0.3065550443248025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}