{"id":"W2971995198","doi":"10.1016/j.vaccine.2019.08.079","title":"Evaluation of recombinant adenovirus vectors and adjuvanted protein as a heterologous prime-boost strategy using HER2 as a model antigen","year":2019,"lang":"en","type":"article","venue":"Vaccine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Antigen; Heterologous; Cytotoxic T cell; Biology; Viral vector; CD8; T cell; Virology; Antibody; Immune system; Immunology; Recombinant DNA; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000623254,0.0005846685,0.0003261651,0.0002260898,0.000100631,0.0003521204,0.0002925762,0.0003901087,0.0004535455],"category_scores_gemma":[0.0003306378,0.0001760397,0.0001909022,0.0002068924,0.0002338951,0.0003170215,0.0001399828,0.0005974723,0.0001563013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000315185,"about_ca_system_score_gemma":0.0003395026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005603456,"about_ca_topic_score_gemma":0.0005208463,"domain_scores_codex":[0.9996779,0.00007371105,0.00004862172,0.00005255236,0.00008726864,0.00005996828],"domain_scores_gemma":[0.9998075,0.00005814758,0.00004050334,0.00002187476,0.00004184449,0.0000301198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005031844,0.0003754659,0.0002871783,0.0001452873,0.00001354002,0.00003773554,0.00003487761,0.0006350188,0.9949333,0.0001638729,0.0000400951,0.00283045],"study_design_scores_gemma":[0.00005097043,0.004067785,0.0005244499,0.000006259221,0.00003180775,0.00009156916,0.00001919725,0.001424794,0.9924935,0.00002508368,0.001259527,0.000005088677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920934,0.0009231029,0.00592482,0.00004938402,0.00006172066,0.0002151704,0.0002312657,0.00004873946,0.0004523806],"genre_scores_gemma":[0.9804688,0.001278534,0.01583859,0.0000362079,0.00001857419,0.0002250097,0.0005533111,0.00002013057,0.001560774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000623254,"threshold_uncertainty_score":0.003296137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02846640926542457,"score_gpt":0.2914407054256987,"score_spread":0.2629742961602741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}