{"id":"W2972006664","doi":"10.1371/journal.pone.0221653","title":"Inflammatory biomarker levels over 48 weeks with dual vs triple lopinavir/ritonavir-based therapy: Substudy of a randomized trial","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; Public Health Ontario; University of Toronto; University Health Network; Toronto General Hospital; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network; AbbVie","keywords":"Medicine; Lopinavir; Biomarker; Internal medicine; Ritonavir; Randomized controlled trial; Lopinavir/ritonavir; Viral load; Gastroenterology; Lamivudine; Oncology; Immunology; Human immunodeficiency virus (HIV); Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005597418,0.001369091,0.003376934,0.00043877,0.0004745907,0.001073087,0.0006420332,0.001439831,0.00244183],"category_scores_gemma":[0.004045958,0.0004812236,0.004358706,0.0006680409,0.0006931961,0.0006669969,0.0005849414,0.001725544,0.0004103291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009001524,"about_ca_system_score_gemma":0.0007804657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001659685,"about_ca_topic_score_gemma":0.003527323,"domain_scores_codex":[0.997103,0.002062234,0.0002350953,0.0002661206,0.0001422895,0.000191145],"domain_scores_gemma":[0.9971711,0.001029533,0.0008788613,0.0004232667,0.0002159238,0.0002814132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9607553,0.003902251,0.007075569,0.001576154,0.01326492,0.00005640231,0.0001102649,0.0003822916,0.001692498,0.00007126774,0.0004476168,0.01066538],"study_design_scores_gemma":[0.8636712,0.08611339,0.02903031,0.0003158352,0.01701538,0.00009671199,0.00009771921,0.001163888,0.0007543649,0.0002271405,0.001479292,0.0000347386],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825777,0.009290808,0.0008820331,0.000436835,0.0003036216,0.003483681,0.001797413,0.00007580616,0.001152104],"genre_scores_gemma":[0.9863645,0.00333936,0.001481809,0.0004621808,0.0003681901,0.005378394,0.001597637,0.00001934023,0.0009886981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005597418,"threshold_uncertainty_score":0.02960229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05465556620784126,"score_gpt":0.2997734392330262,"score_spread":0.245117873025185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}