{"id":"W2972014608","doi":"10.1016/j.jid.2019.07.501","title":"451 Meiomitosis, a novel mechanism of carcinogenesis in head and neck squamous cell carcinomas","year":2019,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Synapsis; Genome instability; Biology; Chromosome instability; Carcinogenesis; Ectopic expression; Head and neck squamous-cell carcinoma; Homologous recombination; Cancer research; DNA repair; Meiosis; Chromosome segregation; Genetics; RAD51; Gene; Cell biology; Chromosome; Cancer; DNA damage; DNA; Head and neck cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003606301,0.0003246747,0.0002413858,0.001031732,0.0005361969,0.0006104602,0.0002424701,0.0005235189,0.001364623],"category_scores_gemma":[0.000232062,0.0002102899,0.0002709112,0.0003517476,0.0004340829,0.0005325825,0.0004278594,0.0003706386,0.0004553116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003374495,"about_ca_system_score_gemma":0.0003416328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004207208,"about_ca_topic_score_gemma":0.0004168697,"domain_scores_codex":[0.9998174,0.00003943799,0.00001833771,0.0000289561,0.00005467267,0.00004118547],"domain_scores_gemma":[0.9998847,0.00002519074,0.00002670264,0.00002451267,0.00002104908,0.00001779863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004166742,0.00005097869,0.009928813,0.0001745443,0.00003836161,0.00330998,0.0001348559,0.0001254281,0.9730824,0.002713213,0.0001876465,0.009837014],"study_design_scores_gemma":[0.00005249769,0.0005993872,0.08656143,0.00003908942,0.00016403,0.02565173,0.0003469042,0.00119088,0.8621778,0.002066083,0.02111973,0.00003047869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733337,0.01361796,0.00548343,0.0002195753,0.00005794584,0.00006676474,0.0002606288,0.0001047778,0.006855366],"genre_scores_gemma":[0.9939452,0.00268123,0.001010794,0.00003695707,0.00001927567,0.00001599107,0.0001382907,0.000005284763,0.002146947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001364623,"threshold_uncertainty_score":0.00456512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01305645179537997,"score_gpt":0.2300772393940536,"score_spread":0.2170207875986736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}