{"id":"W2972020095","doi":"10.21037/jtd.2019.08.88","title":"Hyperprogressive disease with immunotherapy: new directions","year":2019,"lang":"en","type":"letter","venue":"Journal of Thoracic Disease","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Immunotherapy; Disease; Immunology; Internal medicine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002567106,0.000795355,0.001663612,0.0009749157,0.001275032,0.002388289,0.001212232,0.0114389,0.005766599],"category_scores_gemma":[0.008722888,0.0003454722,0.001339291,0.0005388182,0.002337671,0.005934449,0.0010691,0.0224463,0.003429475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002099413,"about_ca_system_score_gemma":0.001903648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007231034,"about_ca_topic_score_gemma":0.002093728,"domain_scores_codex":[0.9981773,0.0005123132,0.0002785975,0.0002493779,0.0006250851,0.0001573744],"domain_scores_gemma":[0.9936537,0.003739353,0.0004205655,0.0002854675,0.001093343,0.0008076455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002223678,0.0002669516,0.003337791,0.001674249,0.0001013257,0.0217366,0.0003451907,0.0005521082,0.001319709,0.02097077,0.6218911,0.3275818],"study_design_scores_gemma":[0.0001641342,0.0002168494,0.001990869,0.002633061,0.00009227989,0.04195819,0.0007787735,0.001160359,0.0002720938,0.04536371,0.9052708,0.00009907667],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001085253,0.11014,0.001100128,0.8630178,0.01973096,0.00003032021,0.00004717968,0.0001016383,0.004746771],"genre_scores_gemma":[0.0152028,0.1892317,0.002470854,0.5000529,0.2873744,0.00010632,0.0001115655,0.00004642656,0.005402907],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0114389,"threshold_uncertainty_score":0.01929122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01507283455267034,"score_gpt":0.3119121871026836,"score_spread":0.2968393525500133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}