{"id":"W2972020095","doi":"10.21037/jtd.2019.08.88","title":"Hyperprogressive disease with immunotherapy: new directions","year":2019,"lang":"en","type":"letter","venue":"Journal of Thoracic Disease","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Immunotherapy; Disease; Immunology; Internal medicine; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001985557,0.0004900433,0.0008787066,0.0004664102,0.00009751967,0.0001186922,0.0003378595,0.0002484886,0.0008988845],"category_scores_gemma":[0.00008797917,0.0003232331,0.001004234,0.0003599637,0.0001665427,0.0002436899,0.00002757892,0.001575705,0.00005520393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003148444,"about_ca_system_score_gemma":0.003793131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002085679,"about_ca_topic_score_gemma":9.380823e-7,"domain_scores_codex":[0.997334,0.0001349118,0.0006893915,0.0003478943,0.001083903,0.0004099041],"domain_scores_gemma":[0.9969965,0.000118174,0.001112023,0.000770363,0.0003982682,0.0006046673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.03172911,0.0003132777,0.004522081,0.001030361,0.001919474,0.008078838,0.00006268904,0.000005117191,0.00006323575,6.923239e-7,0.9092708,0.04300428],"study_design_scores_gemma":[0.002250577,0.0007044575,0.01443836,0.005259979,0.002578721,0.0004946155,0.00002522797,0.000005254109,0.00002935026,0.00005943842,0.973725,0.0004290078],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0106862,0.09288717,0.0001931063,0.8916442,0.002333055,0.001165273,0.0002159756,0.00007619537,0.0007988167],"genre_scores_gemma":[0.009873041,0.00931309,0.001301657,0.8787193,0.01865159,0.00004433416,0.0003184369,0.0004083356,0.08137021],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08357408,"threshold_uncertainty_score":0.999922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01507283455267034,"score_gpt":0.3119121871026836,"score_spread":0.2968393525500133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}