{"id":"W2972063248","doi":"10.1016/j.stem.2019.06.013","title":"Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells","year":2019,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; United States-Israel Binational Science Foundation; New York State Stem Cell Science","keywords":"Genomic imprinting; Biology; Imprinting (psychology); Epigenetics; Embryonic stem cell; Induced pluripotent stem cell; Genetics; Reprogramming; X-inactivation; DNA methylation; Gene; Gene expression; X chromosome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000104487,0.0001314678,0.0001943993,0.0005789991,0.0001073046,0.0003524581,0.0001248812,0.0001323255,0.0009633051],"category_scores_gemma":[0.0002287403,0.0001452591,0.000128434,0.000306117,0.0001990815,0.000105431,0.0002331661,0.0001947212,0.0002268718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001527079,"about_ca_system_score_gemma":0.0001786574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006700069,"about_ca_topic_score_gemma":0.00109494,"domain_scores_codex":[0.9998819,0.00001677249,0.00000996401,0.00002034983,0.0000462928,0.00002477941],"domain_scores_gemma":[0.9998486,0.0000410611,0.00003694993,0.00002208227,0.00002186932,0.0000294624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001241476,0.000003675832,0.002171737,0.00001080174,0.000006556374,0.00009735482,0.00004749426,0.00004032866,0.995413,0.0002388853,0.00001759923,0.001828559],"study_design_scores_gemma":[0.00001857277,0.0001493411,0.1803523,0.000006025626,0.00005154367,0.001969403,0.0001709576,0.000564718,0.8135467,0.0003519926,0.002806958,0.0000115174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969798,0.0006604604,0.0008221287,0.00002868537,0.000007006053,0.000005194593,0.0002977984,0.00003184533,0.00116706],"genre_scores_gemma":[0.9974064,0.0003714737,0.000426868,0.00002469163,0.000004361242,0.000006752035,0.0004880092,0.00001782883,0.001253463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009633051,"threshold_uncertainty_score":0.003222585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007473356786152542,"score_gpt":0.2000458829801031,"score_spread":0.1925725261939505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}