{"id":"W2972072194","doi":"10.1007/s12195-019-00597-w","title":"Tissue Targeting and Ultrasound-Targeted Microbubble Destruction Delivery of Plasmid DNA and Transfection In Vitro","year":2019,"lang":"en","type":"article","venue":"Cellular and Molecular Bioengineering","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Science Foundation of Guangdong Province","keywords":"Microbubbles; Transfection; Gene delivery; Biophysics; Molecular biology; Fluorescence microscope; Genetic enhancement; Fluorescein isothiocyanate; Chemistry; Materials science; Biochemistry; Ultrasound; Fluorescence; Biology; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005612526,0.0003945025,0.0003831362,0.000465255,0.0002568073,0.0003423076,0.0004270436,0.0004438871,0.0009743311],"category_scores_gemma":[0.0003491514,0.0003763052,0.0004883882,0.0004043521,0.0004092745,0.0003082417,0.0002360928,0.0004904681,0.0004049693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006997702,"about_ca_system_score_gemma":0.0005592384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004491996,"about_ca_topic_score_gemma":0.004222732,"domain_scores_codex":[0.9995764,0.00008711144,0.0000369205,0.00007370609,0.00008802858,0.0001378117],"domain_scores_gemma":[0.9997489,0.0001227368,0.00004332474,0.00002983217,0.00002612431,0.00002903564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008123255,0.00002973499,0.00003601814,0.00003698597,0.000004158192,0.00003613301,0.0000431573,0.0002004567,0.9986252,0.000155483,0.00002444714,0.0007270925],"study_design_scores_gemma":[0.000007961079,0.0001103556,0.0003325727,0.000001839749,0.000009068051,0.00003691631,0.000007086242,0.0007571913,0.9981762,0.00002087959,0.0005370509,0.000002916787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9691014,0.004002911,0.02198583,0.0001316932,0.00006218677,0.0001371562,0.000521799,0.0002262271,0.003830682],"genre_scores_gemma":[0.9830376,0.001505063,0.008152349,0.00004850916,0.00001727701,0.0001339275,0.0006073319,0.00007045446,0.006427625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004491996,"threshold_uncertainty_score":0.008931696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002072217823271273,"score_gpt":0.1557859953470047,"score_spread":0.1537137775237334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}