{"id":"W2972169317","doi":"10.1111/jth.14569","title":"No resistance to activated protein C resistance—but choose wisely","year":2019,"lang":"en","type":"letter","venue":"Journal of Thrombosis and Haemostasis","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Health Sciences Centre; University Health Network; Sunnybrook Health Science Centre","funders":"","keywords":"Protein C; Factor V; Activated protein C resistance; Prothrombinase; Point mutation; Factor IXa; Molecular biology; Partial thromboplastin time; Protein S; Thrombin; Factor V Leiden; Chemistry; Mutation; Biochemistry; Biology; Gene; Factor X; Immunology; Medicine; Internal medicine; Venous thrombosis; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002040735,0.0007284956,0.001578581,0.0006976094,0.002471583,0.004056809,0.001152844,0.03580864,0.00593256],"category_scores_gemma":[0.02083193,0.000461021,0.0009672255,0.0004183238,0.005118771,0.005153117,0.001880992,0.03897673,0.004155754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00247886,"about_ca_system_score_gemma":0.001536046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006444523,"about_ca_topic_score_gemma":0.0009305603,"domain_scores_codex":[0.9974039,0.0008410965,0.0003640035,0.0004155877,0.0006495884,0.000325845],"domain_scores_gemma":[0.9927799,0.004066325,0.0005717157,0.0003056717,0.0007248478,0.001551497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003293348,0.0003288382,0.003840605,0.0002838743,0.0001367542,0.04302121,0.0003912102,0.0002911359,0.001760948,0.03157678,0.865002,0.05303738],"study_design_scores_gemma":[0.0006687936,0.000432108,0.00272139,0.001121591,0.0001390954,0.06602746,0.001107672,0.001086618,0.001100808,0.1300734,0.795301,0.0002201604],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001111532,0.003513079,0.0001943639,0.9793674,0.01194385,0.000006888668,0.000009269169,0.0000177513,0.003835821],"genre_scores_gemma":[0.02500458,0.003859695,0.0006624109,0.8358613,0.1279995,0.0000290253,0.00002189824,0.00002645509,0.006535059],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03580864,"threshold_uncertainty_score":0.01984644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05290634470229572,"score_gpt":0.3037960402433085,"score_spread":0.2508896955410128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}