{"id":"W2972217679","doi":"10.3390/molecules24183235","title":"Synthesis of Cyclobutane Analogue 4: Preparation of Purine and Pyrimidine Carbocyclic Nucleoside Derivatives","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Structural isomer; Chemistry; Stereochemistry; Pyrimidine; Stereoselectivity; Sodium methoxide; Steric effects; Sodium borohydride; Alkylation; Thymine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008639561,0.0003138593,0.0003030789,0.0001774058,0.00016448,0.0001812889,0.0002735007,0.0002616946,0.002679734],"category_scores_gemma":[0.0001410389,0.0001094304,0.0001591779,0.0002297935,0.0001081415,0.0001643484,0.0001637004,0.0004532103,0.0008210979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002167314,"about_ca_system_score_gemma":0.0004040547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005588863,"about_ca_topic_score_gemma":0.001266727,"domain_scores_codex":[0.9999321,0.000008957789,0.000005168366,0.0000154542,0.00001490881,0.00002352773],"domain_scores_gemma":[0.9999213,0.000008140623,0.00001202152,0.00001418808,0.00001886864,0.00002543005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001018697,0.00003961954,0.0001008805,0.0001054457,0.000006850497,0.0002161035,0.00003331124,0.0003622892,0.9935781,0.0002915883,0.00007140657,0.005092548],"study_design_scores_gemma":[0.00002594698,0.00037085,0.0006996209,0.000008967226,0.00001384668,0.000226905,0.00001509503,0.0002673921,0.9892595,0.00006696625,0.009035132,0.000009727494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9689687,0.003654354,0.01188944,0.0001925606,0.000143186,0.0002767623,0.001474392,0.0001391348,0.01326149],"genre_scores_gemma":[0.9697149,0.002503655,0.01582626,0.00006973491,0.00002594516,0.0001462063,0.001776194,0.00004709203,0.009890066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002679734,"threshold_uncertainty_score":0.008964598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006755370766639115,"score_gpt":0.2597359736625895,"score_spread":0.2529806028959504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}