{"id":"W2972217679","doi":"10.3390/molecules24183235","title":"Synthesis of Cyclobutane Analogue 4: Preparation of Purine and Pyrimidine Carbocyclic Nucleoside Derivatives","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Structural isomer; Chemistry; Stereochemistry; Pyrimidine; Stereoselectivity; Sodium methoxide; Steric effects; Sodium borohydride; Alkylation; Thymine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000903852,0.0001139681,0.000197617,0.00004989376,0.00001549666,0.000005915547,0.0001268217,0.0001049168,0.00001632376],"category_scores_gemma":[0.0001450531,0.0001019386,0.00006802939,0.00008665127,0.0001482506,0.00000311899,0.0001438272,0.00004838681,0.000002131073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004066472,"about_ca_system_score_gemma":0.00002537352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004069737,"about_ca_topic_score_gemma":0.00000888567,"domain_scores_codex":[0.999183,0.00005222063,0.0002049787,0.0002614324,0.0001448227,0.0001535439],"domain_scores_gemma":[0.999474,0.00002177845,0.00008897641,0.0002740204,0.00008602955,0.00005522247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001476786,0.00005959459,0.002183588,0.0001043333,0.00006498852,0.000001435795,0.00002664445,0.00002003938,0.9959962,0.0002309284,0.00006959897,0.001094978],"study_design_scores_gemma":[0.0002133061,0.0002699773,0.005355006,0.0000322628,0.00001719594,0.000006052939,0.00003354482,0.00009821638,0.9930209,0.00009888159,0.0007506237,0.0001040362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996264,0.001180457,0.0002499076,0.00009320347,0.00001378504,0.000184315,0.00002516387,0.000004986194,0.001984122],"genre_scores_gemma":[0.9987497,0.0002547578,0.0007517411,0.0000229713,0.00001735646,0.00001336628,0.00004306972,0.00001502758,0.0001319883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003171417,"threshold_uncertainty_score":0.4156936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006755370766639115,"score_gpt":0.2597359736625895,"score_spread":0.2529806028959504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}