{"id":"W2972311843","doi":"10.1101/770487","title":"Mechanotransduction of strain regulates an invasive phenotype in newly transformed epithelial cells","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; LightMachinery (Canada); University of Ottawa","funders":"Hokkaido University; Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Mechanotransduction; Cell biology; Phenotype; Actin; Biology; Epithelium; Dynamics (music); Adhesion; Cell; Cytoskeleton; Strain (injury); Chemistry; Anatomy; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006107568,0.0001385533,0.0001537728,0.0001617021,0.0001388393,0.0002761955,0.0001254539,0.0001709681,0.0009808523],"category_scores_gemma":[0.00007139069,0.000120132,0.0001871982,0.0001086546,0.0001488453,0.0001275299,0.0001862172,0.0003453062,0.0002292552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001889339,"about_ca_system_score_gemma":0.00008238136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004635516,"about_ca_topic_score_gemma":0.0003702117,"domain_scores_codex":[0.9998989,0.00001544341,0.00000884375,0.00001296999,0.00003781888,0.00002610656],"domain_scores_gemma":[0.9998804,0.00002570578,0.00002687589,0.00001908771,0.00001765843,0.00003025564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002706198,0.00001812996,0.0001855307,0.000006927989,0.000001440575,0.00004050384,0.00001310792,0.00002944405,0.9993394,0.00004665045,0.00000999415,0.0002818848],"study_design_scores_gemma":[0.000007602369,0.0002144735,0.01587446,0.000003062827,0.000006076161,0.0002507101,0.0001013794,0.002335397,0.980283,0.00005825268,0.0008602463,0.000005334758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982326,0.0001986783,0.0008581093,0.00002396318,0.000008865022,0.000006949177,0.00006753979,0.00002581413,0.0005775522],"genre_scores_gemma":[0.9985861,0.0001017007,0.0004158854,0.00001456908,0.000002703071,0.000009168114,0.00008699991,0.000006045698,0.0007768919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009808523,"threshold_uncertainty_score":0.003281295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014799220206695,"score_gpt":0.2144370747957662,"score_spread":0.2042890825936992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}