{"id":"W2972314280","doi":"10.1002/pro.3729","title":"Structural perspectives on HIV‐1 Vif and APOBEC3 restriction factor interactions","year":2019,"lang":"en","type":"review","venue":"Protein Science","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; Canada Research Chairs","keywords":"Human immunodeficiency virus (HIV); Genetics; Computational biology; Biology; Evolutionary biology; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003221864,0.0006830964,0.0006856981,0.001446187,0.000254249,0.0007059877,0.0006393977,0.0009292671,0.002745609],"category_scores_gemma":[0.0003064005,0.0002216648,0.0002266536,0.001801758,0.0003621833,0.001113316,0.0004912702,0.001346355,0.001697135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007592377,"about_ca_system_score_gemma":0.0008066872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001061611,"about_ca_topic_score_gemma":0.001895737,"domain_scores_codex":[0.9999061,0.00001267916,0.00001128382,0.00001802537,0.00003782117,0.00001416705],"domain_scores_gemma":[0.9998816,0.00005108453,0.00001607017,0.00000337993,0.00003196072,0.00001584165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009802408,0.00006459131,0.0001991836,0.01490708,0.00005621732,0.0003399653,0.0001163413,0.0005393969,0.007623534,0.01238806,0.03706739,0.9266002],"study_design_scores_gemma":[0.00000566051,0.00005430165,0.00046998,0.001335128,0.00002870877,0.0006508982,0.00004051409,0.00006500378,0.0006030989,0.002044566,0.9946931,0.000008909565],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001723567,0.997409,0.0001125877,0.0003141839,0.0003388334,0.000002229415,0.00001362121,0.000004702087,0.00163237],"genre_scores_gemma":[0.0007910362,0.9974131,0.0001519581,0.0002233816,0.0002542644,0.000003363951,0.0000311994,0.000001275175,0.001130542],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002745609,"threshold_uncertainty_score":0.009184957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07887681596142088,"score_gpt":0.384193333846866,"score_spread":0.3053165178854452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}