{"id":"W2972314280","doi":"10.1002/pro.3729","title":"Structural perspectives on HIV‐1 Vif and APOBEC3 restriction factor interactions","year":2019,"lang":"en","type":"review","venue":"Protein Science","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; Canada Research Chairs","keywords":"Human immunodeficiency virus (HIV); Genetics; Computational biology; Biology; Evolutionary biology; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001537078,0.00023438,0.0004568189,0.0003769021,0.0004400418,0.00008175713,0.0003187062,0.00012187,0.0003406287],"category_scores_gemma":[0.0002450603,0.0001526524,0.0001074216,0.0003818424,0.0006162646,0.0001990443,0.0001451571,0.000534714,0.002544584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003037461,"about_ca_system_score_gemma":0.0004100594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004932637,"about_ca_topic_score_gemma":0.000004244791,"domain_scores_codex":[0.9985335,0.0001695616,0.0001891957,0.0006337967,0.00009703404,0.0003768509],"domain_scores_gemma":[0.9992712,0.0001232368,0.0001341793,0.0003448974,0.00007820976,0.00004827156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002464476,0.0000612363,0.00001596068,0.0007068317,0.0001091606,0.000005125992,0.0004156744,1.18094e-7,0.002418713,0.001320688,0.0001586642,0.9947632],"study_design_scores_gemma":[0.0003069661,0.0004104307,0.000183161,0.001990377,0.00007173164,0.00009133225,0.0002582555,9.772378e-7,0.0006325041,0.00004557528,0.9957278,0.0002808444],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002488447,0.9941152,0.000009360037,0.00006147883,0.0003309556,0.001473541,0.0002162805,0.0000396474,0.001265104],"genre_scores_gemma":[0.008152855,0.9858623,0.00007624342,0.000003987501,0.00003373635,0.0002004824,0.00006646688,0.00001314208,0.005590743],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9955692,"threshold_uncertainty_score":0.9982321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07887681596142088,"score_gpt":0.384193333846866,"score_spread":0.3053165178854452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}