{"id":"W2972363761","doi":"10.1128/jvi.01185-19","title":"The Education of NK Cells Determines Their Responsiveness to Autologous HIV-Infected CD4 T Cells","year":2019,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University; Université de Montréal; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Government of Canada","keywords":"Biology; Interleukin 21; Lymphokine-activated killer cell; Major histocompatibility complex; Interleukin 12; Immunology; NK-92; Human leukocyte antigen; MHC class I; Natural killer cell; Flow cytometry; Janus kinase 3; Cell biology; Cytotoxic T cell; Immune system; T cell; Antigen; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001418465,0.0001519416,0.0002578358,0.0001487755,0.0001411861,0.0004090662,0.0001382478,0.0002122147,0.001999849],"category_scores_gemma":[0.0004343445,0.0001191922,0.0001412776,0.00007811222,0.0001976584,0.0002280653,0.0003259553,0.0005580936,0.0004123073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001587842,"about_ca_system_score_gemma":0.0001149001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001602085,"about_ca_topic_score_gemma":0.0001935532,"domain_scores_codex":[0.999743,0.00005872871,0.00001885281,0.00004329582,0.00002866858,0.0001073279],"domain_scores_gemma":[0.9997116,0.0001191792,0.00002862992,0.00005218376,0.00002782741,0.00006060712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000634602,0.000127831,0.008732793,0.00005515204,0.000007790991,0.0001871631,0.0001586404,0.0002878598,0.9824595,0.0002483358,0.00005513547,0.0070452],"study_design_scores_gemma":[0.0001256867,0.002682537,0.08787739,0.00006954283,0.00007350233,0.003091536,0.0008055559,0.003420217,0.8964342,0.0007491237,0.00465018,0.00002053882],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981074,0.0002780596,0.0002798981,0.00001728367,0.000006035095,0.00001337264,0.00003647717,0.00001021698,0.001251283],"genre_scores_gemma":[0.9990221,0.0001135476,0.000178786,0.00001730139,0.000004995181,0.00001117689,0.00004919743,0.000003239483,0.0005996762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001999849,"threshold_uncertainty_score":0.006690204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005984125460156911,"score_gpt":0.2346419075915269,"score_spread":0.22865778213137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}