{"id":"W2972518525","doi":"10.1016/j.ijrobp.2019.06.594","title":"The Genomic Landscape of Anal Cancer and Its Relationship to Clinical Outcomes: An Exploratory Analysis of NRG Oncology/RTOG 98-11","year":2019,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Colorectal and Anal Carcinomas","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Medicine; Oncology; PTEN; Cancer; Internal medicine; Cisplatin; Cancer research; Radiation therapy; PI3K/AKT/mTOR pathway; Chemotherapy; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003336052,0.0001994583,0.0003523488,0.0008022002,0.0004634636,0.0006131039,0.0003702041,0.0003115242,0.00305936],"category_scores_gemma":[0.001459353,0.0001811075,0.0004563313,0.001557934,0.0002904365,0.0002619927,0.0009683536,0.0004263991,0.0005209516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002444961,"about_ca_system_score_gemma":0.0004190225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005818917,"about_ca_topic_score_gemma":0.007968171,"domain_scores_codex":[0.9996201,0.00008408761,0.0000209229,0.0001022685,0.00005091108,0.0001216465],"domain_scores_gemma":[0.9991688,0.000195317,0.0002676621,0.0001238484,0.00009101699,0.0001534058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005703251,0.00005460473,0.9921846,0.00002434842,0.000120451,0.0001594767,0.0003060681,0.0001152153,0.00225069,0.00007752937,0.0004163142,0.003720411],"study_design_scores_gemma":[0.000008898161,0.0001470456,0.9975697,0.000008104557,0.00006638899,0.0003718071,0.0005499048,0.0001432235,0.000180568,0.00006277226,0.0008878607,0.000003760772],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973743,0.0001324701,0.000119542,0.00005137451,0.000001563285,0.00001039822,0.001768387,0.000006157939,0.0005357764],"genre_scores_gemma":[0.9976327,0.00006511765,0.0001412903,0.00004921065,0.000004411389,0.00001551142,0.001684956,0.00001653483,0.0003901946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005818917,"threshold_uncertainty_score":0.0115701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05556480097997721,"score_gpt":0.3921811788950093,"score_spread":0.3366163779150321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}