{"id":"W2972576119","doi":"10.3390/genes10090710","title":"HLA-DQB1 and HLA-DRB1 Variants Confer Susceptibility to Latent Autoimmune Diabetes in Adults: Relative Predispositional Effects among Allele Groups","year":2019,"lang":"en","type":"review","venue":"Genes","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; Alberta Innovates - Health Solutions","keywords":"Autoimmune diabetes; Medicine; Odds ratio; Diabetes mellitus; Human leukocyte antigen; Meta-analysis; Internal medicine; Bonferroni correction; Allele; Relative risk; Immunology; Gastroenterology; Endocrinology; Type 1 diabetes; Confidence interval; Antigen; Gene; Genetics; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000318349,0.0004821784,0.001057338,0.00009832172,0.00006817874,0.00004986152,0.0002470649,0.0005938436,0.0000260981],"category_scores_gemma":[0.0001318095,0.0004257807,0.0002944794,0.0001660983,0.00009444483,0.0000126085,0.0003120417,0.0002262319,0.00003582683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005724292,"about_ca_system_score_gemma":0.0001281829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004572474,"about_ca_topic_score_gemma":0.0001226555,"domain_scores_codex":[0.9976937,0.000278483,0.0004908546,0.0008570757,0.0001760422,0.0005039165],"domain_scores_gemma":[0.9990584,0.00008876419,0.0002276606,0.0004167114,0.00008555105,0.0001228665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001703191,0.001137606,0.1230962,0.03196613,0.003247359,0.00002468168,0.0003663951,0.0001139902,0.003677444,0.000381741,0.002618296,0.8331999],"study_design_scores_gemma":[0.005640641,0.002491231,0.2544491,0.0244629,0.001820695,0.000005079578,0.0001527874,0.000232326,0.0006009159,0.0004118121,0.7057937,0.003938795],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1795174,0.8183881,0.00001189247,0.00002848634,0.0002682147,0.001327108,0.0002407835,0.00001677359,0.0002012576],"genre_scores_gemma":[0.03365593,0.9623206,0.0001015449,0.00010329,0.0001514194,0.0003245172,0.00270323,0.00007588736,0.0005635365],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8292611,"threshold_uncertainty_score":0.9998194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008462447994806555,"score_gpt":0.246774697115816,"score_spread":0.2383122491210095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}