{"id":"W2972776431","doi":"10.3390/cells8091071","title":"Mechanistic Connections between Endoplasmic Reticulum (ER) Redox Control and Mitochondrial Metabolism","year":2019,"lang":"en","type":"review","venue":"Cells","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; China Scholarship Council","keywords":"Endoplasmic reticulum; Mitochondrion; Cell biology; Calnexin; Unfolded protein response; Oxidative phosphorylation; Biology; Mitochondrial membrane transport protein; Chemistry; Biochemistry; Inner mitochondrial membrane; Calreticulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001053051,0.0006001789,0.001511906,0.0001082972,0.000125584,0.00009152699,0.0003157431,0.0006365235,0.00005987228],"category_scores_gemma":[0.0001445417,0.0005144072,0.000595285,0.0001046063,0.0001391328,0.000004294025,0.0001676994,0.0003116674,0.0001723731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000181806,"about_ca_system_score_gemma":0.0002757279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001964464,"about_ca_topic_score_gemma":0.000004478024,"domain_scores_codex":[0.9975739,0.0002514504,0.0005934885,0.0009248421,0.0001943537,0.0004619873],"domain_scores_gemma":[0.9983428,0.0001538244,0.0003522716,0.0007623674,0.00007873506,0.000309988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006860943,0.00121176,0.0001267772,0.09893444,0.01426732,0.0004642368,0.0001537837,0.00007499793,0.09248157,0.01634458,0.1119793,0.6632752],"study_design_scores_gemma":[0.001198973,0.0001195779,0.000002295533,0.0007867958,0.003589294,0.00005398127,0.00001120279,0.000008742593,0.002411856,0.00008771661,0.9911214,0.0006082029],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000529306,0.9933152,0.0007912056,0.00001556026,0.001621034,0.001266472,0.001406416,0.00002817293,0.001026619],"genre_scores_gemma":[0.00212024,0.9934185,0.0002309161,0.00005976842,0.001441733,0.0001671737,0.0008725818,0.0001005941,0.001588494],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8791421,"threshold_uncertainty_score":0.9997308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01600301948850472,"score_gpt":0.2726470602559364,"score_spread":0.2566440407674316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}