{"id":"W2972820854","doi":"10.1016/j.coph.2019.08.001","title":"Small talk: microbial metabolites involved in the signaling from microbiota to brain","year":2019,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":138,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Medical Research Council Canada; Research Councils UK","keywords":"Neuroinflammation; Gut–brain axis; Microbiome; Biology; Neuroscience; Neurotransmission; Gut flora; Central nervous system; Gastrointestinal tract; Receptor; Cell biology; Biochemistry; Bioinformatics; Immunology; Inflammation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007239502,0.0005848946,0.001293632,0.0003649123,0.00005978787,0.00004513154,0.001080966,0.0005831012,0.000111024],"category_scores_gemma":[0.00005515059,0.0004731151,0.0003873053,0.0004516081,0.00007813001,0.000004244175,0.0004153379,0.0009056391,0.0001500163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001055348,"about_ca_system_score_gemma":0.0006237449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009397144,"about_ca_topic_score_gemma":0.00008436953,"domain_scores_codex":[0.9959844,0.00121241,0.0009886748,0.001016499,0.00008422499,0.0007138452],"domain_scores_gemma":[0.998795,0.0002315736,0.0003365411,0.0004715306,0.00005117067,0.0001141553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001595673,0.0008515905,0.0001392851,0.01604519,0.0002639439,0.000007728084,0.0006537649,0.00002234001,0.5495871,0.0000438217,0.1998752,0.2323504],"study_design_scores_gemma":[0.0009790768,0.00009350254,0.00004006326,0.00224551,0.0001269848,0.00001370124,0.00003571889,0.000001393286,0.001053538,0.000006847654,0.9949263,0.0004773611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007070516,0.9797027,0.00003199712,0.0004276934,0.009946002,0.002221827,0.0005751273,0.000009929633,0.00001417798],"genre_scores_gemma":[0.0002107815,0.9919316,0.0001561845,0.001175325,0.001899238,0.0002483044,0.004263741,0.00006538379,0.00004946486],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7950511,"threshold_uncertainty_score":0.9997721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1410123238196255,"score_gpt":0.4198558671833694,"score_spread":0.2788435433637439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}