{"id":"W2972922274","doi":"10.1186/s12866-019-1577-5","title":"Missense mutations in a transmembrane domain of the Komagataeibacter xylinus BcsA lead to changes in cellulose synthesis","year":2019,"lang":"en","type":"article","venue":"BMC Microbiology","topic":"Advanced Cellulose Research Studies","field":"Materials Science","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Tech University","funders":"Natural Sciences and Engineering Research Council of Canada; University of New England; University of Manitoba","keywords":"Bacterial cellulose; Cellulose; Biochemistry; Mutant; Transmembrane domain; Chemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001350586,0.0005281623,0.0002685697,0.00030418,0.0002125566,0.0002907305,0.0002484693,0.0005216417,0.002085608],"category_scores_gemma":[0.0003442216,0.0001658723,0.0004326601,0.0003262367,0.0003814946,0.0001216563,0.0003676393,0.0004655691,0.0007218771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003289594,"about_ca_system_score_gemma":0.0002550096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001020157,"about_ca_topic_score_gemma":0.0007583777,"domain_scores_codex":[0.9998025,0.00005017723,0.00003342428,0.00003157849,0.00005627161,0.00002614755],"domain_scores_gemma":[0.9995744,0.0001310167,0.000157196,0.00003676,0.00002570889,0.00007499026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000227003,0.00006339554,0.0005254346,0.0000503408,0.00002261412,0.001044365,0.00003003906,0.0002152167,0.9955958,0.0001529584,0.00007690403,0.001995876],"study_design_scores_gemma":[0.00007338388,0.0004958833,0.01752511,0.0000331142,0.00008504604,0.003522895,0.0001443131,0.00326054,0.9715762,0.0001765664,0.003073971,0.00003300914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965545,0.0001921874,0.001778131,0.00009517498,0.00006137637,0.00003228754,0.000550427,0.0001000629,0.0006357734],"genre_scores_gemma":[0.9967429,0.0001535227,0.001435154,0.00004688456,0.00001488644,0.00001966686,0.0004141261,0.00004170055,0.001131187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002085608,"threshold_uncertainty_score":0.006977022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01807070302523335,"score_gpt":0.2636415179723093,"score_spread":0.2455708149470759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}