{"id":"W2972967880","doi":"10.1177/2054358119871936","title":"Three Optimized Methods for In Situ Quantification of Progenitor Cell Proliferation in Embryonic Kidneys Using BrdU, EdU, and PCNA","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Kidney Health and Disease","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Progenitor cell; Proliferating cell nuclear antigen; Nephron; Biology; Bromodeoxyuridine; Cell biology; Progenitor; Kidney; Molecular biology; Stem cell; Pathology; Immunohistochemistry; Immunology; Medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004456035,0.003358651,0.001442555,0.003653216,0.001234212,0.001388259,0.002078387,0.002139187,0.002998901],"category_scores_gemma":[0.00368816,0.001741495,0.001480134,0.002077802,0.001300261,0.0009622024,0.001167901,0.00188205,0.001707667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001348841,"about_ca_system_score_gemma":0.001694057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001267887,"about_ca_topic_score_gemma":0.005402985,"domain_scores_codex":[0.9925523,0.001393255,0.0009398661,0.001786744,0.002854535,0.0004734339],"domain_scores_gemma":[0.9958622,0.001291029,0.0007736394,0.0005724509,0.001275172,0.0002254442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001727401,0.0000769961,0.0005215734,0.0005373074,0.00005359143,0.00004483996,0.0001200752,0.0004485731,0.9813266,0.0003285955,0.0002373957,0.01613168],"study_design_scores_gemma":[0.00002491711,0.0001964233,0.002359046,0.00005048822,0.0001205122,0.0002772761,0.00003453893,0.00253228,0.9878414,0.0001400037,0.006353796,0.0000692103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.07427862,0.003412964,0.912492,0.0001941212,0.0002606816,0.001937152,0.0009031263,0.004314551,0.002206633],"genre_scores_gemma":[0.03471744,0.00196553,0.9532509,0.0001196609,0.00003534945,0.00436729,0.001570213,0.0006960835,0.003277529],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.004456035,"threshold_uncertainty_score":0.02356601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01708102011093804,"score_gpt":0.3148134161817921,"score_spread":0.2977323960708541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}