{"id":"W2973031262","doi":"10.1128/jb.00430-19","title":"Induction of <i>Rhodobacter capsulatus</i> Gene Transfer Agent Gene Expression Is a Bistable Stochastic Process Repressed by an Extracellular Calcium-Binding RTX Protein Homologue","year":2019,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Rhodobacter; Biology; Horizontal gene transfer; Gene; Mutant; Extracellular; Genetics; Regulation of gene expression; Gene expression; Point mutation; Genome; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001208598,0.0004107066,0.000231659,0.000167234,0.0001295361,0.0003175091,0.0002134538,0.0001995062,0.0007103294],"category_scores_gemma":[0.0002153355,0.000130309,0.0002279357,0.0001138813,0.0002295564,0.0001320052,0.0003477275,0.0004834629,0.0003397684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004864524,"about_ca_system_score_gemma":0.0002118878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001167109,"about_ca_topic_score_gemma":0.001067687,"domain_scores_codex":[0.9997655,0.0000310032,0.00001549346,0.00005886493,0.00007910167,0.00005007665],"domain_scores_gemma":[0.9998061,0.00003032746,0.00007057057,0.00003513808,0.00002441798,0.00003346236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001108254,0.000004149174,0.00006809847,0.000005011762,7.364083e-7,0.00001039975,0.000003497252,0.00002140254,0.9995499,0.00003985079,0.00000946384,0.0002763925],"study_design_scores_gemma":[0.000003952969,0.00007289031,0.003208359,0.000001999242,0.000003039037,0.00006321097,0.00001484059,0.0006433201,0.9952869,0.00002942354,0.000667792,0.000004179079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992222,0.0005453316,0.004201173,0.0001510741,0.00002954721,0.00002486393,0.0001998276,0.000286523,0.002339627],"genre_scores_gemma":[0.9962387,0.0001724048,0.001714026,0.00003114475,0.000007158068,0.00001885443,0.0001849646,0.00004386885,0.001588888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001167109,"threshold_uncertainty_score":0.003529429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01363034858712291,"score_gpt":0.2421851577465942,"score_spread":0.2285548091594713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}