{"id":"W2973075108","doi":"10.1101/766147","title":"SET8 localization to chromatin flanking DNA damage is dependent on RNF168 ubiquitin ligase","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chromatin; Ubiquitin ligase; Ubiquitin; DNA damage; DNA repair; Cell biology; Biology; DNA; DNA ligase; Genetics; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009726342,0.000304944,0.0002065264,0.0002004102,0.0001979549,0.0002779459,0.0002810875,0.0003005146,0.002677792],"category_scores_gemma":[0.0001312427,0.0001789032,0.000284436,0.0000929892,0.0001755692,0.0001871414,0.0002745934,0.000387981,0.001305515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004047245,"about_ca_system_score_gemma":0.0001256716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004369402,"about_ca_topic_score_gemma":0.0006251631,"domain_scores_codex":[0.9998989,0.00001154924,0.000008483468,0.00002901444,0.00003219705,0.00001987591],"domain_scores_gemma":[0.9999092,0.00001390412,0.00002130916,0.00001487851,0.00001359648,0.00002712036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008027387,0.000007692181,0.0002567502,0.00002718152,0.000005305821,0.00007577502,0.000007047805,0.00003121275,0.9987217,0.0001263196,0.0000584905,0.0006022496],"study_design_scores_gemma":[0.000007762159,0.00003670634,0.004764559,0.000004463252,0.000004594307,0.0003348011,0.00001025389,0.0007425811,0.9920635,0.0000653234,0.001961689,0.000003754545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879825,0.001632786,0.006557764,0.0001425137,0.00006889694,0.00002027031,0.0005505433,0.0002247854,0.002819974],"genre_scores_gemma":[0.9873771,0.0003362318,0.003908984,0.00004190853,0.00001064024,0.00002622448,0.001125104,0.00004257689,0.007131288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002677792,"threshold_uncertainty_score":0.008958101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009370593167101142,"score_gpt":0.223917823525719,"score_spread":0.2145472303586179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}