{"id":"W2973090041","doi":"10.1016/j.aquatox.2019.105285","title":"Underlying mechanisms of reproductive toxicity caused by multigenerational exposure of 2, bromo-4, 6-dinitroaniline (BDNA) to Zebrafish (Danio rerio) at environmental relevant levels","year":2019,"lang":"en","type":"article","venue":"Aquatic Toxicology","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; University of Toronto","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Biology; Danio; Estrogen receptor; Zebrafish; Fecundity; Population; Internal medicine; Endocrinology; Gene; Andrology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000205858,0.0004312125,0.0002344258,0.0003320055,0.0002692352,0.0002588888,0.000507063,0.0005586373,0.001156309],"category_scores_gemma":[0.0001157688,0.0001812894,0.0003870189,0.000091573,0.0003870907,0.0003376635,0.0002762938,0.0003280756,0.000153047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005238368,"about_ca_system_score_gemma":0.0003957604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001834164,"about_ca_topic_score_gemma":0.002246318,"domain_scores_codex":[0.9999005,0.00001343694,0.000008316962,0.00002894989,0.0000263763,0.00002246835],"domain_scores_gemma":[0.9998964,0.00001162185,0.00004158103,0.00001000985,0.0000234847,0.00001685237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001038387,0.00003315459,0.0007864339,0.00009419965,0.00001323812,0.0001917312,0.00004346741,0.0001384455,0.9961345,0.0005502535,0.00005396677,0.001856856],"study_design_scores_gemma":[0.00003370435,0.000861824,0.0587008,0.00004537939,0.0001035064,0.0009447501,0.0001888674,0.001772868,0.9322568,0.001611495,0.003452131,0.00002799526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9750525,0.008692317,0.009407558,0.0004709174,0.00007529563,0.0001241881,0.0007487005,0.0002277249,0.005200733],"genre_scores_gemma":[0.9895216,0.004034843,0.00202989,0.0001393471,0.00001438358,0.00009815794,0.0003530844,0.000008802626,0.003799804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001834164,"threshold_uncertainty_score":0.003868222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02229355705198748,"score_gpt":0.2613329808129974,"score_spread":0.23903942376101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}