{"id":"W2973118395","doi":"10.1101/769422","title":"Green, orange, red, and far-red optogenetic tools derived from cyanobacteriochromes","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Light effects on plants","field":"Agricultural and Biological Sciences","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Toronto","funders":"","keywords":"Phycocyanobilin; Chromophore; Biliverdin; Optogenetics; Far-red; Orange (colour); Limiting; Chemistry; Protein engineering; Synechocystis; Red light; Biophysics; Phycocyanin; Biology; Photochemistry; Cyanobacteria; Biochemistry; Genetics; Gene; Bacteria; Botany; Heme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003097818,0.0007146276,0.0008375976,0.00005295804,0.000190262,0.0005648257,0.0008620658,0.0007780423,0.0003219265],"category_scores_gemma":[0.0001308339,0.0003651722,0.000164966,0.0003049649,0.0001237289,0.0002317337,0.0009204621,0.0005264654,0.0001663399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001002072,"about_ca_system_score_gemma":0.00008073478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006613557,"about_ca_topic_score_gemma":0.00008061853,"domain_scores_codex":[0.9966975,0.0002606352,0.0005003909,0.001447824,0.0004318525,0.0006617329],"domain_scores_gemma":[0.9981588,0.0003282505,0.0004122505,0.0005300388,0.000214541,0.0003560897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004841268,0.00005770287,0.03483012,0.00009597522,0.0001237565,0.00004258981,0.000004885339,0.000001959459,0.964569,0.000006404896,0.0001478588,0.00007130697],"study_design_scores_gemma":[0.0002801026,0.00009416715,0.7507182,0.0002609895,0.00008242593,3.00826e-8,0.000001909986,0.00004712665,0.2423432,0.000002698465,0.00545605,0.0007131189],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938245,0.001306621,0.000009602677,0.0007693508,0.0008877704,0.001073122,0.001770572,0.0003453007,0.00001319756],"genre_scores_gemma":[0.9974312,0.0007004959,0.0007078837,0.0003763285,0.0006345624,0.0001108397,0.000009976543,0.00001640703,0.00001235466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7222258,"threshold_uncertainty_score":0.99988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01826480601169538,"score_gpt":0.1981446568988491,"score_spread":0.1798798508871537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}