{"id":"W2973123957","doi":"10.1097/coc.0000000000000599","title":"Phase I/II Trial of Neoadjuvant Oregovomab-based Chemoimmunotherapy Followed by Stereotactic Body Radiotherapy and Nelfinavir For Locally Advanced Pancreatic Adenocarcinoma","year":2019,"lang":"en","type":"article","venue":"American Journal of Clinical Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Quest University Canada","funders":"National Cancer Institute","keywords":"Medicine; Nelfinavir; Gemcitabine; Chemoimmunotherapy; Pancreatic cancer; Internal medicine; FOLFIRINOX; Adenocarcinoma; Oncology; Surgery; Gastroenterology; Cancer; Irinotecan; Immunotherapy; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001345138,0.001531817,0.001776971,0.0003949134,0.000491661,0.0008341292,0.0009471601,0.001341067,0.004598052],"category_scores_gemma":[0.0007617446,0.0007085152,0.0009073819,0.0003543154,0.00105661,0.000715853,0.0003284161,0.003302625,0.0008658156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001182033,"about_ca_system_score_gemma":0.001927401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001071208,"about_ca_topic_score_gemma":0.002965625,"domain_scores_codex":[0.9996164,0.0001772669,0.00002102668,0.00008420374,0.00002743194,0.0000737442],"domain_scores_gemma":[0.9993739,0.00008817835,0.000108254,0.00006894168,0.00003655011,0.0003241929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8678221,0.07424112,0.002539202,0.000388954,0.0006579781,0.00008893392,0.0001335197,0.0008428414,0.024465,0.000191528,0.001773399,0.02685556],"study_design_scores_gemma":[0.7026933,0.2885787,0.003257417,0.00002765653,0.0002389725,0.00008735222,0.00003152953,0.0005933601,0.002999116,0.0001239259,0.001353982,0.00001472231],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992007,0.001259294,0.0004327857,0.000395274,0.0002171241,0.003304678,0.0007259964,0.00007503722,0.001582846],"genre_scores_gemma":[0.9872348,0.001007372,0.001534978,0.0007860493,0.000189601,0.004290059,0.001727166,0.00003101614,0.003198962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004598052,"threshold_uncertainty_score":0.01538199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04319597588248913,"score_gpt":0.4525099512132602,"score_spread":0.409313975330771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}