{"id":"W2973137482","doi":"10.1016/j.bbmt.2019.09.013","title":"Dual T Cell Depletion with Anti-Thymocyte Globulin and Post-Transplant Cyclophosphamide Results in Low Rates of Cytokine Release Syndrome in Peripheral Blood Haplo-Hematopoietic Stem Cell Transplantation","year":2019,"lang":"en","type":"letter","venue":"Biology of Blood and Marrow Transplantation","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Anti-thymocyte globulin; Haematopoiesis; Hematopoietic stem cell transplantation; Stem cell; Immunology; Cytokine; Cyclophosphamide; Transplantation; Peripheral blood; Globulin; Internal medicine; Chemotherapy; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007816602,0.0004697263,0.0006567849,0.0002870655,0.0007354421,0.001111854,0.0005186539,0.007582822,0.001384067],"category_scores_gemma":[0.004084846,0.0002558178,0.000492313,0.0002287722,0.0008030648,0.0005713598,0.0002309152,0.004355018,0.0008453489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001123773,"about_ca_system_score_gemma":0.0004291747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006225034,"about_ca_topic_score_gemma":0.00103389,"domain_scores_codex":[0.9994065,0.0002307073,0.00006604651,0.00006789125,0.0001327803,0.00009611701],"domain_scores_gemma":[0.9977822,0.001612264,0.0001695742,0.0001083559,0.0001191182,0.0002085093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.005907181,0.001436575,0.03612174,0.0002259005,0.0002543043,0.5768312,0.0004697918,0.001330952,0.02684276,0.01233511,0.2492291,0.08901536],"study_design_scores_gemma":[0.00223439,0.00424763,0.05396304,0.0003250406,0.0003602246,0.593835,0.0004892018,0.01528563,0.033807,0.01529537,0.2799667,0.0001908537],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2462944,0.005819692,0.004293618,0.6827688,0.01817721,0.0001312962,0.0002954503,0.0005726268,0.04164701],"genre_scores_gemma":[0.7485122,0.003131291,0.002174048,0.1983193,0.02103189,0.0001124787,0.0001937143,0.0001476242,0.02637732],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007582822,"threshold_uncertainty_score":0.008153558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008808940330552397,"score_gpt":0.2314573830089409,"score_spread":0.2226484426783885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}