{"id":"W2973321661","doi":"10.3310/hta23480","title":"Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT","year":2019,"lang":"en","type":"article","venue":"Health Technology Assessment","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; Queen's University; La Jolla Pharmaceutical Company; ResMed; University of Southampton; National Institute for Health and Care Research; GlaxoSmithKline; Intensive Care Foundation; Health Technology Assessment Programme; Guy's and St Thomas' Charity; Wellcome Trust; Department of Health and Social Care; Swedish Orphan Biovitrum; Queen's University Belfast; Bayer","keywords":"Medicine; Randomized controlled trial; Mechanical ventilation; Weaning; Intensive care; Ventilator weaning; Intensive care medicine; Emergency medicine; Surgery; Anesthesia; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003198255,0.0002454149,0.0006431017,0.0002615135,0.0001458038,0.0000139865,0.0002057328,0.000273845,0.00004364725],"category_scores_gemma":[0.00009977174,0.0001647551,0.00007627923,0.0003498301,0.00007510639,0.00007172863,0.00008375351,0.0005670753,0.00001823655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005092853,"about_ca_system_score_gemma":0.001711837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001523957,"about_ca_topic_score_gemma":0.0009063881,"domain_scores_codex":[0.9980857,0.00006883711,0.0005241217,0.000552234,0.0002802558,0.0004888207],"domain_scores_gemma":[0.9981109,0.000194609,0.0003849026,0.0006099988,0.0005941024,0.0001054852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"qualitative","study_design_scores_codex":[0.0228541,0.001861392,0.7437421,0.005931245,0.001163785,0.0005972362,0.03013324,0.0001544523,0.09463478,0.02591213,0.003467093,0.06954842],"study_design_scores_gemma":[0.07166331,0.03553822,0.2715798,0.01284917,0.0004099131,0.0002467362,0.4022154,0.005222322,0.1749066,0.006376696,0.01748543,0.001506383],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9523433,0.00009755944,0.005764137,0.008858376,0.0002297053,0.03240486,0.0000327215,0.0001521119,0.0001172713],"genre_scores_gemma":[0.9799519,0.00001573606,0.007508385,0.003014826,0.00004975582,0.009225491,0.000164908,0.00003930863,0.00002975606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4721623,"threshold_uncertainty_score":0.6718518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0231490656750943,"score_gpt":0.3421751920821766,"score_spread":0.3190261264070823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}