{"id":"W2973372114","doi":"10.3390/cancers11091403","title":"Hypoxia Downregulates LPP3 and Promotes the Spatial Segregation of ATX and LPP1 During Cancer Cell Invasion","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Autotaxin; Lysophosphatidic acid; Invadopodia; Hypoxia (environmental); Cancer research; Cell biology; Cancer cell; Biology; Tumor microenvironment; Cell migration; Cell; Metastasis; Cancer; Receptor; Chemistry; Biochemistry; Tumor cells","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003973374,0.000136091,0.0001293517,0.0001029754,0.0001437018,0.0001738756,0.00006472829,0.0001279586,0.0006835695],"category_scores_gemma":[0.00005127109,0.00009356398,0.0001116173,0.00009530607,0.0001442291,0.0001456753,0.0001443717,0.0002718709,0.0001945662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001976865,"about_ca_system_score_gemma":0.0001686489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009692947,"about_ca_topic_score_gemma":0.0009180006,"domain_scores_codex":[0.9999502,0.000006319438,0.000002659108,0.00001065145,0.00001258322,0.00001754745],"domain_scores_gemma":[0.9999586,0.000004801714,0.0000128526,0.000002888692,0.000005553134,0.00001518389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000961011,0.000004440166,0.0002606839,0.0000122378,0.000001333205,0.00003275106,0.00001148081,0.00002049593,0.9989257,0.00004922863,0.00002208576,0.0005634383],"study_design_scores_gemma":[0.00001126418,0.0001448618,0.03941889,0.000004046259,0.000009744489,0.0003139223,0.00006606566,0.00085979,0.9566571,0.00008244601,0.002427812,0.000004124656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954789,0.001576913,0.001667858,0.00007802722,0.00001046177,0.00000862608,0.0001658104,0.00004071314,0.0009727427],"genre_scores_gemma":[0.9968623,0.0006058282,0.0006916335,0.00003831042,0.000006131326,0.00002195692,0.0001639484,0.000007995004,0.001601932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009692947,"threshold_uncertainty_score":0.002286792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005117914394559318,"score_gpt":0.2050598492099145,"score_spread":0.1999419348153552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}