{"id":"W2973489729","doi":"10.1093/gbe/evz197","title":"A High-Resolution View of Adaptive Event Dynamics in a Plasmid","year":2019,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Human Genome Research Institute; Pennsylvania State University; Alfred P. Sloan Foundation; National Institutes of Health; National Science Foundation","keywords":"Plasmid; Biology; Genetics; Escherichia coli; Population; Experimental evolution; Gene; Chromosome; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002081214,0.000116859,0.0001774126,0.00006777555,0.00002990454,0.000001911919,0.00008259775,0.0002410053,0.00001745282],"category_scores_gemma":[0.00001862503,0.0001162046,0.00004617857,0.0001055613,0.0001139067,0.000003525832,0.0000854489,0.00007920513,0.00001646253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000948727,"about_ca_system_score_gemma":0.00005916793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001257583,"about_ca_topic_score_gemma":0.0005889891,"domain_scores_codex":[0.9991278,0.00009178406,0.0002410069,0.0002910433,0.00004530988,0.0002030512],"domain_scores_gemma":[0.999626,0.000008477403,0.00009679043,0.0001784104,0.00005142555,0.00003892376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00093595,0.0002659672,0.30911,0.0001149129,0.0001310104,0.000001070697,0.0001065427,0.01158034,0.552793,0.1224326,0.00007746922,0.002451066],"study_design_scores_gemma":[0.002494302,0.002170082,0.9232433,0.00004919956,0.00003264852,0.00003167562,0.0003969337,0.05923823,0.0009531671,0.007855897,0.00303429,0.0005002237],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804407,0.002760482,0.01589798,0.00007952799,0.0001708339,0.000230748,0.00006304884,0.000006392872,0.0003503195],"genre_scores_gemma":[0.9980039,0.0005140014,0.000822669,0.00004793402,0.00004152212,0.0000122982,0.0003409101,0.000007897657,0.0002088818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6141334,"threshold_uncertainty_score":0.4738687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004354302216958667,"score_gpt":0.221718685813012,"score_spread":0.2173643835960533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}