{"id":"W2973514824","doi":"10.1016/s1470-2045(19)30569-8","title":"Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial","year":2019,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":536,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Institute for Health and Care Research; Institute of Cancer Research; Metropolitan Museum of Art; Cancer Research UK; Manchester Biomedical Research Centre; Accuray; Cilag; NIHR Bristol Biomedical Research Centre; National Health Insurance Service; Royal Marsden NHS Foundation Trust","keywords":"Medicine; Radiation therapy; Prostate cancer; Dose fractionation; Clinical endpoint; Androgen deprivation therapy; Prostate; Internal medicine; Randomized controlled trial; Oncology; Urology; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006971678,0.001960338,0.003553563,0.0005274362,0.0004813711,0.001508957,0.001402772,0.002623036,0.009881525],"category_scores_gemma":[0.006938993,0.0006314896,0.003564732,0.0008474039,0.001889186,0.001608778,0.0007627699,0.0034813,0.001108967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009606059,"about_ca_system_score_gemma":0.001834338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006173278,"about_ca_topic_score_gemma":0.001181019,"domain_scores_codex":[0.9961501,0.002874596,0.0002038695,0.0003163609,0.0002262288,0.0002287807],"domain_scores_gemma":[0.9957345,0.001525884,0.001262796,0.000399238,0.0002360553,0.0008415999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.984857,0.002995244,0.0001942629,0.0007989762,0.0007448265,0.00001624531,0.00004457861,0.0002002812,0.001422835,0.00009753407,0.0005505015,0.008077751],"study_design_scores_gemma":[0.9583184,0.04000428,0.0005532128,0.00004997625,0.0003409617,0.00001599015,0.000008898018,0.0001084344,0.0001377917,0.000101557,0.000351757,0.000008695344],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9584841,0.01694226,0.002127172,0.001752688,0.001071775,0.01093437,0.002181753,0.0002395802,0.006266269],"genre_scores_gemma":[0.9650199,0.007647378,0.003579431,0.002738518,0.001099222,0.01432839,0.002017551,0.00006785929,0.003501762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009881525,"threshold_uncertainty_score":0.03687018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06750216261748353,"score_gpt":0.4349405895770075,"score_spread":0.367438426959524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}