{"id":"W2973606086","doi":"10.1016/j.cobme.2019.09.006","title":"Multiscale models of kidney function and diseases","year":2019,"lang":"en","type":"review","venue":"Current Opinion in Biomedical Engineering","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Function (biology); Nephron; Computer science; Neuroscience; Kidney; Computational biology; Biology; Evolutionary biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005844162,0.0001811222,0.000416235,0.000148152,0.00000790239,0.00000445248,0.00007707848,0.0002262143,0.00000532685],"category_scores_gemma":[0.00003132324,0.0001589459,0.0001298409,0.0001233941,0.00003620148,0.000004442957,0.00003915804,0.0001152628,0.000001281574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001203884,"about_ca_system_score_gemma":0.00009122115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.14228e-7,"about_ca_topic_score_gemma":3.106038e-8,"domain_scores_codex":[0.9991282,0.00001364558,0.0003420104,0.0002556125,0.000128005,0.0001325863],"domain_scores_gemma":[0.999603,0.000009725902,0.00008105357,0.0001372657,0.00001631927,0.0001526859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001868482,0.0001661854,0.00005158264,0.08204887,0.00007912354,1.980316e-7,0.000014669,0.0005014524,0.0001411895,0.0003162426,0.001558427,0.9151034],"study_design_scores_gemma":[0.0002886876,0.00005299547,0.00005451303,0.008160716,0.00006194165,0.000001877775,0.000001480797,0.004194814,0.000003222829,0.00001373652,0.9869856,0.0001804495],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003226368,0.9824252,0.01433224,0.000005762829,0.002854341,0.0002274812,0.0001106884,0.000009228062,0.000002865405],"genre_scores_gemma":[0.0005374317,0.9957399,0.00004089794,0.000001784836,0.0004308128,0.00003336293,0.003181837,0.00002250209,0.0000114389],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9854271,"threshold_uncertainty_score":0.6481624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04281949025203038,"score_gpt":0.3108819581981158,"score_spread":0.2680624679460855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}