{"id":"W2973743789","doi":"10.1016/j.celrep.2019.08.044","title":"The ArfGAP Drongo Promotes Actomyosin Contractility during Collective Cell Migration by Releasing Myosin Phosphatase from the Trailing Edge","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institutes of Natural Sciences; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research; Cancer Research Society; National Institute for Health and Care Research; University of Missouri","keywords":"Guanine nucleotide exchange factor; Cell biology; Myosin; GTPase; Biology; Cell migration; Phosphatase; Small GTPase; Cell; Phosphorylation; Genetics; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002594169,0.0001884041,0.0001430497,0.00001202732,0.000479556,0.0001511783,0.0001440093,0.0001405769,0.00005669369],"category_scores_gemma":[0.0001451354,0.0001328713,0.0001401193,0.00008423589,0.00004214655,0.00001593013,0.0000721609,0.000237716,0.00001228132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005440659,"about_ca_system_score_gemma":0.0001568967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000303372,"about_ca_topic_score_gemma":0.0001637599,"domain_scores_codex":[0.9985958,0.0001004867,0.0003707188,0.0004960785,0.0001672467,0.0002696457],"domain_scores_gemma":[0.9986757,0.000108789,0.000354616,0.000678964,0.0001124146,0.00006952775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008193438,0.0001054565,0.001143254,0.000008333625,0.00002997837,0.00001090165,0.0001613309,0.00001014796,0.9946893,0.000003593447,0.003342555,0.0004132488],"study_design_scores_gemma":[0.0002489317,0.00006162873,0.001453216,0.00001624169,0.00003117078,0.00002385315,0.000293077,0.0002999676,0.908466,0.00006444028,0.08888745,0.0001540301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917169,0.004517663,0.0003162746,0.0002339529,0.0006609668,0.0006121286,0.00004327235,0.0000164795,0.001882352],"genre_scores_gemma":[0.9941127,0.0003485316,0.00004941878,0.00007245414,0.0001501635,0.00003375649,0.0003753539,0.00002880205,0.004828825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08622327,"threshold_uncertainty_score":0.5418335,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004648941710314417,"score_gpt":0.2046725257712012,"score_spread":0.2000235840608868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}