{"id":"W2973896221","doi":"10.3390/v11090869","title":"Bacterial Virus Lambda Gpd-Fusions to Cathelicidins, α- and β-Defensins, and Disease-Specific Epitopes Evaluated for Antimicrobial Toxicity and Ability to Support Phage Display","year":2019,"lang":"en","type":"article","venue":"Viruses","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Epitope; Antimicrobial peptides; Capsid; Defensin; Biology; Peptide; Antimicrobial; Bacteriophage; Cathelicidin; Phage display; Amino acid; Biochemistry; Microbiology; Molecular biology; Chemistry; Escherichia coli; Gene; Antigen; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002000258,0.0002330387,0.0002623327,0.00005147457,0.0002632901,0.0001689983,0.0001179147,0.00006794409,0.001334978],"category_scores_gemma":[0.00008682378,0.0002081078,0.00004928781,0.0001147213,0.0001402236,0.0003457807,0.0003993732,0.00008193293,0.0002929758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007017661,"about_ca_system_score_gemma":0.00002036317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006738986,"about_ca_topic_score_gemma":0.001145855,"domain_scores_codex":[0.9986089,0.00005809134,0.0002591647,0.0006360988,0.0001052123,0.0003324844],"domain_scores_gemma":[0.9990687,0.0001079436,0.0000576061,0.0002973794,0.00001864548,0.0004497219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003923463,0.0001443202,0.005134562,0.0000210305,0.000008687179,0.000002313624,0.0003753424,0.000008661251,0.9831735,0.00001784367,0.007354892,0.003366495],"study_design_scores_gemma":[0.001323516,0.0005627814,0.4860321,0.00006173985,0.00007921666,0.00002629459,0.00007231698,0.00005200102,0.2293381,0.00004325262,0.2817833,0.0006254412],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961349,0.00003337754,0.00008028769,0.0006763206,0.0004603947,0.001194938,0.00130785,0.00004233498,0.00006964092],"genre_scores_gemma":[0.9967071,0.0001366682,0.0007644225,0.001895714,0.00009949469,0.00003529927,0.00004106659,0.00002743259,0.000292787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7538354,"threshold_uncertainty_score":0.9995779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0244619047553273,"score_gpt":0.2763728187464779,"score_spread":0.2519109139911506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}