{"id":"W2974140699","doi":"10.1016/s2215-0366(19)30340-2","title":"First episode mania: we should have intervened earlier","year":2019,"lang":"en","type":"letter","venue":"The Lancet Psychiatry","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Pfizer UK; Cancer Council Victoria; Bristol-Myers Squibb Canada; H. Lundbeck A/S; Servier; Otsuka Pharmaceutical; Dainippon Sumitomo Pharma; Bushfire Cooperative Research Centre; Australian Rotary Health; Alberta Livestock and Meat Agency; National Institute for Health and Care Research; Simons Foundation Autism Research Initiative; Janssen Biotech; Sunovion; National Health and Medical Research Council; Stanley Foundation; Eli Lilly and Company; Roche; Michael Smith Health Research BC; GlaxoSmithKline; Geelong Region Medical Research Foundation","keywords":"Mania; Psychology; Bipolar disorder; Medicine; Psychiatry; Lithium (medication)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004337517,0.001009642,0.002326156,0.0009978717,0.009754515,0.00614827,0.002199068,0.1245923,0.01602731],"category_scores_gemma":[0.04259031,0.001066612,0.002075569,0.0007269803,0.006320585,0.009243798,0.003642868,0.1103928,0.006611017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007630488,"about_ca_system_score_gemma":0.01168709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01626306,"about_ca_topic_score_gemma":0.02941406,"domain_scores_codex":[0.9951215,0.001371009,0.0007220914,0.0005743231,0.0009584319,0.001252592],"domain_scores_gemma":[0.9811183,0.007544802,0.001404525,0.0005036537,0.002472271,0.00695642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001329824,0.00007646131,0.001454186,0.00020728,0.00006816206,0.0050864,0.0005757068,0.00007052362,0.000294149,0.005212228,0.9751995,0.0116225],"study_design_scores_gemma":[0.00105588,0.0002169021,0.00498115,0.00403028,0.0002303706,0.01133251,0.004067123,0.0005367819,0.0003318396,0.03949291,0.9334022,0.0003220346],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001721155,0.001152093,0.0000352116,0.9838154,0.01396567,0.000004317313,0.000009104961,0.000007785985,0.0008384312],"genre_scores_gemma":[0.002066466,0.0008090701,0.00008807312,0.9742507,0.02110769,0.00001307166,0.00000736517,0.000009825075,0.00164774],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1245923,"threshold_uncertainty_score":0.0553633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04689459153010334,"score_gpt":0.2988186772875892,"score_spread":0.2519240857574859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}