{"id":"W2974140699","doi":"10.1016/s2215-0366(19)30340-2","title":"First episode mania: we should have intervened earlier","year":2019,"lang":"en","type":"letter","venue":"The Lancet Psychiatry","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Pfizer UK; Cancer Council Victoria; Bristol-Myers Squibb Canada; H. Lundbeck A/S; Servier; Otsuka Pharmaceutical; Dainippon Sumitomo Pharma; Bushfire Cooperative Research Centre; Australian Rotary Health; Alberta Livestock and Meat Agency; National Institute for Health and Care Research; Simons Foundation Autism Research Initiative; Janssen Biotech; Sunovion; National Health and Medical Research Council; Stanley Foundation; Eli Lilly and Company; Roche; Michael Smith Health Research BC; GlaxoSmithKline; Geelong Region Medical Research Foundation","keywords":"Mania; Psychology; Bipolar disorder; Medicine; Psychiatry; Lithium (medication)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001812673,0.0005295082,0.001019366,0.0001029029,0.0001334333,0.00005384323,0.0005370235,0.0008215073,0.000933582],"category_scores_gemma":[0.00001117538,0.0003230662,0.000531719,0.0001017264,0.00009853183,0.00004061852,0.0001327955,0.002732268,0.001842975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009616309,"about_ca_system_score_gemma":0.00008752295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002243468,"about_ca_topic_score_gemma":0.001356101,"domain_scores_codex":[0.9978285,0.00009862469,0.0003751704,0.0005677687,0.0004583748,0.0006715874],"domain_scores_gemma":[0.9978036,0.0000981043,0.0001896047,0.001809399,0.00004196906,0.00005729711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001191503,0.0001506324,0.09536294,0.001000505,0.0007426905,0.00003200167,0.0001678124,9.364729e-7,3.830478e-7,0.00008225803,0.9018111,0.0005296185],"study_design_scores_gemma":[0.002511976,0.0002841169,0.02725342,0.000890982,0.0008094746,0.0001729961,0.00004474515,0.00001899056,0.000003535303,0.001454497,0.9662231,0.0003321655],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0003957471,0.02696372,0.00004112823,0.9439374,0.003267883,0.0008468309,0.0001547007,0.0001494084,0.02424324],"genre_scores_gemma":[0.006128642,0.001722487,0.0008637882,0.9170854,0.02575738,0.0001596138,0.0005860969,0.0002294889,0.04746711],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06810951,"threshold_uncertainty_score":0.9999797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04689459153010334,"score_gpt":0.2988186772875892,"score_spread":0.2519240857574859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}