{"id":"W2974248079","doi":"10.1002/ejoc.201901142","title":"Synthesis of LacNAcLe<sup>x</sup>‐ and DimLe<sup>x</sup>‐BSA Conjugates and Binding to Anti‐Polymeric Le<sup>x</sup> mAbs","year":2019,"lang":"en","type":"article","venue":"European Journal of Organic Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Glycoconjugate; Stereochemistry; Tetrasaccharide; Linker; Glycoside; Monomer; Residue (chemistry); Molecule; Iodide; Disaccharide; Polysaccharide; Biochemistry; Polymer; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002449994,0.0004496053,0.0002303437,0.0002113622,0.0001526417,0.0002619037,0.0003190183,0.0002980801,0.001583121],"category_scores_gemma":[0.0001883785,0.0001982333,0.0002185359,0.0002414703,0.0001711231,0.0001943115,0.0002845068,0.00051069,0.0009829066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003603314,"about_ca_system_score_gemma":0.0001583607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000336189,"about_ca_topic_score_gemma":0.0004514785,"domain_scores_codex":[0.9998447,0.00003092545,0.00001427909,0.00002708253,0.00004662373,0.0000364024],"domain_scores_gemma":[0.999858,0.00002172265,0.00003166317,0.00002582583,0.00002780755,0.00003492619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004174116,0.00002320004,0.00003777793,0.00002539863,0.000003595413,0.0000265428,0.00001341107,0.0001612512,0.9978231,0.0001556582,0.00003885436,0.001649481],"study_design_scores_gemma":[0.000009724119,0.000155063,0.0004936957,0.000002121021,0.000005618353,0.00005849023,0.000004743552,0.0004823478,0.995862,0.00002776677,0.002894865,0.000003620452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9702417,0.001396983,0.02374368,0.0001244995,0.00005427044,0.0001823771,0.0005752835,0.0002102143,0.00347102],"genre_scores_gemma":[0.9581071,0.001270881,0.02701964,0.0001794454,0.0000308753,0.0001855581,0.001747438,0.0001104439,0.01134861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001583121,"threshold_uncertainty_score":0.005296111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007230784349265907,"score_gpt":0.1896743060962608,"score_spread":0.1824435217469949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}