{"id":"W2974292424","doi":"10.1073/pnas.1909311116","title":"The gut microbiome regulates host glucose homeostasis via peripheral serotonin","year":2019,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute; McMaster University","funders":"Medical Research Council; Canadian Institutes of Health Research; National Health and Medical Research Council; Government of Canada","keywords":"Microbiome; Gut flora; Glucose homeostasis; Serotonin; Homeostasis; Biology; Regulator; Gut microbiome; Endocrinology; Immunology; Bioinformatics; Biochemistry; Diabetes mellitus; Insulin resistance; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001125287,0.0001433212,0.0002311754,0.0001490335,0.0001359636,0.0004564741,0.00009066275,0.0002496749,0.001101715],"category_scores_gemma":[0.0001681888,0.00009116097,0.0001340794,0.00008875669,0.0002665371,0.0001390907,0.0002452102,0.0003870464,0.0002288996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002582986,"about_ca_system_score_gemma":0.0001860125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008188116,"about_ca_topic_score_gemma":0.001340749,"domain_scores_codex":[0.9999019,0.00002802373,0.000005362774,0.00001875369,0.00001993288,0.00002609972],"domain_scores_gemma":[0.9998693,0.00001494926,0.00003806417,0.00001001098,0.00001812549,0.00004956542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003939523,0.00002250289,0.002817294,0.00007637691,0.00001960302,0.0001199219,0.00002390742,0.00007008805,0.9872847,0.0002678553,0.0001411283,0.008762619],"study_design_scores_gemma":[0.0001654798,0.001790112,0.4439927,0.0001670611,0.0001707707,0.001098179,0.0004023525,0.003298162,0.5378645,0.001225061,0.009783019,0.0000425668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806461,0.01051947,0.003636517,0.0008874742,0.00008939106,0.00001956897,0.0003434483,0.0001133095,0.003744616],"genre_scores_gemma":[0.9930467,0.003522185,0.001960494,0.0001806277,0.00002081775,0.00001548415,0.0001180579,0.00001180822,0.001123937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001101715,"threshold_uncertainty_score":0.003685534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139048406672908,"score_gpt":0.2782050711468854,"score_spread":0.2643002304795946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}