{"id":"W2974384578","doi":"10.1104/pp.19.00629","title":"Catalytic Plasticity of Germacrene A Oxidase Underlies Sesquiterpene Lactone Diversification","year":2019,"lang":"en","type":"article","venue":"PLANT PHYSIOLOGY","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Germacrene; Sesquiterpene; Sesquiterpene lactone; Biology; Biochemistry; Asteraceae; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005590041,0.0001451035,0.0002132943,0.00003068205,0.0000332159,0.000004596251,0.0002036023,0.0001576396,0.00005447286],"category_scores_gemma":[0.00004124947,0.0001283113,0.00007218499,0.00005375719,0.0000912106,0.000004386278,0.0001096964,0.00005351088,0.0000452859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000894831,"about_ca_system_score_gemma":0.00003922168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002370321,"about_ca_topic_score_gemma":0.000009281217,"domain_scores_codex":[0.9991762,0.00003815002,0.0001768094,0.0003247526,0.00007909006,0.0002049796],"domain_scores_gemma":[0.9994746,0.00006225241,0.0001326818,0.0002413299,0.00003916089,0.00004999132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004125519,0.00009782667,0.001019446,0.00008718815,0.0000720029,0.000001797461,0.00001689361,0.00003802858,0.9976126,0.0000501688,0.0004771939,0.000114284],"study_design_scores_gemma":[0.0003252325,0.000156099,0.01165649,0.00002037472,0.00002780314,0.00002859912,0.00003798276,0.0001261969,0.9858057,0.00003016794,0.001624529,0.000160769],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983509,0.00007772203,0.00004052821,0.00004149722,0.00007490523,0.0001049407,0.0006440815,0.00001110703,0.0006543288],"genre_scores_gemma":[0.9977871,0.00008899627,0.00006145373,0.00007900527,0.00008411337,0.000004678493,0.001606179,0.00000758833,0.0002809322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01180686,"threshold_uncertainty_score":0.5232381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01017536533951081,"score_gpt":0.2121988776063373,"score_spread":0.2020235122668265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}